Onnit Active B Complete Review – Is It An Effective Brain Booster?

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By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

onnit active b complete review

In today’s world, most of us could use more energy, both from a physical and mental standpoint. Afternoon crashes and general feelings of fatigue are all too common.

Sometimes, nutrient deficiencies can be related to these issues, such as deficiencies in B-complex vitamins, which is why supplementation is often a recommended course of action…but quality matters! So, it’s important to do your research to know you’re getting the right pick when it comes to vitamins and supplements.

We did the research for you on this one, though. So, let’s take a closer look at a supplement option called Onnit Active B Complete. This supplement is designed to provide your body with the vitamins it needs for better mental and physical energy. In this Onnit Active B review, we’ll dive into this supplement’s ingredients, benefits, claims, pricing, and more so you can find out if it’s truly worth adding to your routine.

Without anything further, let’s get started with this Onnit Active B Complete review!

Active B Complete Supplement

About Onnit Active B Complete

Active B Complete is a B-Complex supplement created by Onnit. Specifically, it includes methylated B-vitamins, which are supposed to be more easily absorbed and used by the body, leading to better results.

With its inclusion of these active B-vitamins, including a few registered trademarked forms, Onnit Active B Complex is designed to be a cut above other B-complex supplements and, thus, deliver superior results. 

Onnit Active B Complete Benefits

Based on their various roles in the body, the B-vitamins in Onnit Active B Complete are designed to give you a wide variety of mental and physical benefits

Mental Energy and Related Benefits

First, Active B Complete is advertised to mitigate stress and decrease fatigue, in addition to boosting mental energy and focus. Furthermore, it is also designed to enhance your mood and overall mental well-being. 

Physical Energy and Related Benefits

Additionally, you are to expect a boost in physical energy when taking Active B Complete. Increased energy production may lead to better workouts, work efficiency, and more. Plus, Active B Complete is supposed to aid in detoxification processes, helping you feel better from the inside out. 

Active B Complete Benefits - Mental and Physical Energy

But will Onnit Active B Complete actually provide you with all of these benefits? Read on to find out!

Onnit Active B Complete Ingredients

In each serving, which is one capsule, Onnit Active B Complete contains the following: 

  • Thiamine [Vit.B1] (1.5mg)
  • Riboflavin [Vit.B2] (1.7mg)
  • Niacin [Vit.B3] (20mg NE)
  • Vitamin B6 (2mg)
  • Folate [Vit.B9] (667mcg DFE)
  • Vitamin B12 (6mcg)
  • Biotin [Vit.B7] (300mcg)
  • Pantothenic Acid [Vit.B5] (10mg)
  • Vitamin B1 Derivative [Benfotiamine] (150mg)
Onnit Active B Complete Supplement Facts

So, as you can see, Onnit Active B Complex contains all 8 of the B-Complex vitamins. Now, let’s see what they offer. 


Thiamine or vitamin B1 is primarily involved in the production of energy from carbohydrates and fats. It has a pivotal role in energy metabolism, especially in the brain, but it also is needed critically for digestion and heart health. It also plays a role in detoxification. Interestingly, Active B Complex contains both vitamin B1 and a trademarked form of vitamin B1 derivative called BenfoPure. This specific form is proven to have enhanced bioavailability and is very effective at helping the body break down excess sugar and reducing elevated glucose levels. 


Riboflavin, or vitamin B2, is also heavily involved in energy metabolism. It is important for the production of antioxidants, mainly glutathione, and it also is involved in iron metabolism and is needed for overall cardiovascular and nervous system health. The form included in Active B Complex is also very quickly and easily absorbed. 


Niacin, or vitamin B3, is primarily involved in energy production and antioxidant factors. Niacin can help convert the major macronutrients (proteins, fats, carbohydrates) into energy. The form of niacin included (inositol hexanicotinate) is also less likely to produce flushing. 

Vitamin B6

Vitamin B6 is one of the most well-known B-vitamins, and for good reason. It is necessary for the formation of red blood cells, carbohydrate metabolism, liver detoxification, and is a potent regulator of the brain and nervous system functioning. Vitamin B6 is also necessary for the production of some key neurotransmitters, such as GABA, serotonin, and dopamine. Without enough vitamin B6, your risk for many things increases, such as depression, inflammation, liver problems, ADHD, anemia, and others. Active B Complete included the biologically active form pyridoxal 5-phosphate, which is more bioavailable. 


Folate, or vitamin B9, also has numerous roles. Folate is very important for overall brain and nervous system health, and it is necessary for nerve transmission and the production of neurotransmitters, including dopamine and serotonin. This vitamin also regulates homocysteine levels and red blood cell production and is important for overall cardiovascular health. Without enough folate, your risk for depression, cognitive decline, high blood pressure, and other problems increases. The specific form in Active B Complete is Quatrefolic, which is shown to have enhanced bioavailability to other folate supplements.

Vitamin B12

Vitamin B12 is in tight competition with vitamin B6 in terms of the most well-known B-complex vitamin. Like most B-complex vitamins, it is involved in energy production. But it’s also unique in that it can be stored by the body for a long time, yet it is also difficult to absorb. It is involved in red blood cell production and oxygen transport, and it also plays a key role in DNA methylation as well as overall brain health and neurotransmitter production. Finally, it plays a key role in aerobic energy metabolism. Deficiencies are related to fatigue, tinnitus, depression, memory loss, and other not-so-fun aliments! Since B12 is hard to absorb, it is good that Active B Complex included methylcobalamin, which is the biologically active form. 


Biotin, sometimes referred to as vitamin B7 or even vitamin H, plays important functions in carbohydrate and fat metabolism. It is also involved in insulin functioning and is important for healthy skin and hair, which is why it’s also a popular ingredient in collagen and hair support supplements like Isagenix Collagen Elixir and Hairburst Healthy Hair Vitamins. Deficiencies in Biotin are associated with skin and hair concerns (e.g., dermatitis, skin rash), diabetes, and other problems.  

Pantothenic Acid

Finally, there is pantothenic acid, or vitamin B5. Pantothenic acid is necessary for the metabolism of carbohydrates, fats, and proteins, as well as the production of certain hormones. Deficiencies are related to acne, fatigue, and high cholesterol, among other things.

Does Onnit Active B Complete Work?

Alight, let’s zoom out a little bit now from the individual ingredients and analyze Active B Complex as a whole.

So, will it work effectively? Very likely. 

Onnit Active B Complete includes all B-Complex vitamins and, more importantly, includes forms of these vitamins that are highly active and bioavailable. This means that they simply will exert greater effects and lead to more benefits. Many people today are deficient in at least one B-complex vitamin, and supplementing with pretty high doses is often needed for optimal physical and mental performance, especially in the case of a deficiency and/or strenuous physical and/or mental exertion. 

Onnit Active B Complete - In Hand

Claims vs. Reality

Onnit Active B Complete is advertised to benefit many aspects of physical and mental health, such as energy production and increased metabolism, lower fatigue, improved cognition, better mood and lower stress, better physical endurance and energy, and detoxification enhancement.

Quite an array of benefits, and honestly, you may experience all of these to some degree. Just look again at what all of the B-complex vitamins do. They are almost all involved in energy metabolism, and a few are tightly involved in brain and nervous system health, detoxification, neurotransmitter production, insulin and glucose regulation, antioxidant production, and more!

Therefore, it is likely that this supplement will offer a wide variety of physical and mental health benefits, at least at some level. It probably won’t cure you of anything, but it will assist you in navigating your current health concerns, especially ones related to B-vitamin deficiencies. 

Who is Onnit Active B Complete Best For?

The people who would benefit most from Onnit Active B Complete are those who are deficient in one or more of the B-complex vitamins. But since you may not want (or be able) to get tested, here are some characteristics that increase the likelihood of supplementation benefits: 

  • High stress
  • History of poor diet
  • Sleep problems
  • Low energy and fatigue
  • Mood disorders
  • Diabetes or insulin-related issues
  • Cardiovascular issues

If more than three of these factors apply to you, you’d likely benefit at least some from this product. 

Onnit Active B Complete - B complex vitamins

Is Onnit Active B Complete Safe?

B-Complex vitamins are generally safe to consume as they are water-soluble and can be excreted through urine when taken in excess. However, below are some potential side effects:

  • Mood swings, depression, anxiety, and panic attacks
  • Restlessness and insomnia
  • Stomach cramps, nausea, vomiting, and diarrhea
  • Headache, dizziness, tingling sensations

Again, these aren’t likely to occur, and given the moderate dose of the ingredients, any side effects shouldn’t be too concerning. 

Where to Buy Onnit Active B Complete

You can buy Onnit Active B Complete by going directly to the official Onnit website here.

Onnit Active B Complete - Website

In each bottle of Onnit Active B Complete, you get 30 servings (30 capsules). The price per bottle for a one-time purchase is $18.95.

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They also offer a Subscribe and Save option which will save you 15%, bringing the price down to $16.11 per bottle. So, you’re looking at around 50 to 60 cents per serving, which is very affordable for most people.

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Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.

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