Research-Based

PROBIO-50 Review – Is This Cutler Nutrition Probiotic Worth Buying?

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By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

probio 50 review

Gut health optimization has taken center stage in health and wellness circles, and rightfully so. Many people struggle with digestive issues—bloating, nausea, constipation, and other uncomfortable symptoms. Since the gut connects to numerous bodily systems, an unhealthy gut often means compromised overall health.

Within gut health optimization, enhancing microbiome health stands out as one of the most effective strategies, and numerous supplements claim to support this goal. One such supplement is PROBIO-50 by Cutler Nutrition.

Does this probiotic deliver results? How effective are the ingredients? Is it worth the investment? In this PROBIO-50 review, we’ll answer these questions and more. Let’s dive in and discover whether PROBIO-50 merits your purchase!

cutler nutrition probio 50

About Cutler Nutrition PROBIO-50

Cutler Nutrition PROBIO-50 (referred to as PROBIO-50 throughout) is a multi-strain probiotic blend supplement created by Cutler Nutrition. This supplement company, founded by former NFL quarterback Jay Cutler, has developed various supplements beyond PROBIO-50, including Prevail Pre-Workout, Amplify Pre-Workout, and Total Iso Protein.

PROBIO-50 contains over 50 billion CFUs (colony-forming units), but its unique feature is the inclusion of CoreBiome, a specific postbiotic ingredient designed to maximize probiotic effectiveness. This supplement aims to increase beneficial bacteria in your gut while enhancing overall digestive function through CoreBiome, creating benefits for both digestive and general health.

PROBIO-50 Benefits

Through its influence on gut flora, the microbiome, and intestinal function, PROBIO-50 is marketed to enhance digestion, eliminate bloating, boost immunity, reduce inflammation, and increase energy levels.

cutler nutrition probio 50 improved digestion

Improved Digestion/Reduced Bloating

The combination of probiotics and CoreBiome promises to enhance all aspects of digestive health, including better nutrient absorption and reduced gas or diarrhea. It’s also designed to eliminate bloating, particularly that caused by heavy meals or indigestion.

Improved Immunity

Given the intricate relationship between gut and immune health, PROBIO-50 is designed to strengthen immune system function and promote greater overall wellness.

Lower Inflammation

CoreBiome in PROBIO-50 is formulated to regulate inflammatory responses and combat oxidative stress, leading to reduced intestinal inflammation and enhanced gut health.

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Increased Energy

Finally, PROBIO-50 aims to boost energy levels by improving nutrient absorption and eliminating waste products more efficiently. Essentially, it’s designed to enhance energy by helping your body maximize the nutrients you consume.

These benefits address common concerns many people face today. But how likely is PROBIO-50 to deliver on these promises? Read on to discover!

PROBIO-50 Ingredients

PROBIO-50 comes in capsule form with a serving size of 3 capsules. Here’s what each serving contains:

  • Tributyrin (as CoreBiome 30%) (1000mg)
    • Yields 300mg
  • Vegan Multi-Strain Probiotics (50 Billion CFU), which contains these strains:

     

    • Lactobacillus acidophilus
    • Bifidobacterium breve
    • Lactobacillus fermentum
    • Lactobacillus rhamnosus
    • Lactobacillus gasseri
    • Lactobacillus plantarum
    • Bifidobacterium lactus
    • Lactobacillus casei
    • Lactobacillus paracasei
    • Lactobacillus salivarius
    • Bifidobacterium longum
    • Bifidobacterium bifidum
    • Bifidobacterium infantis
    • Streptococcus thermophilus

While that’s quite a list, simply understand these represent various beneficial probiotic strains.

cutler nutrition probio 50 supplement

CoreBiome

PROBIO-50 stands out among probiotic supplements by including CoreBiome, a form of tributyrin. Tributyrin is a short-chain fatty acid (SCFA) that functions as a postbiotic—essentially a byproduct of the fermentation process carried out by probiotics.

There are also prebiotics, which serve as food for probiotics. So the process works like this: probiotics consume prebiotics and produce postbiotics. Yes, that’s many “biotics” to distinguish, but that’s the basic gut ecosystem at work.

Postbiotics, including tributyrin, offer numerous benefits. Research shows postbiotic supplementation enhances immune function and significantly reduces inflammation. Additionally, postbiotics strengthen gastrointestinal integrity and help address leaky gut and other digestive problems.

Furthermore, postbiotics indirectly benefit probiotics and the overall gut microbiome.

While more research is needed, current evidence suggests postbiotics effectively address various conditions, including inflammation, IBS and other digestive issues, neurological disorders, and even certain cancers. CoreBiome represents a well-researched, effective form of postbiotics, capable of reaching both small and large intestines with high bioavailability.

Vegan Multi-Strain Probiotics

The second key ingredient is the Vegan Multi-Strain Probiotics blend, containing 14 different probiotic strains totaling approximately 50 billion CFUs.

Probiotics are beneficial bacteria that inhabit the gastrointestinal system and directly influence gut health, which impacts overall wellness. They’re essential for warding off harmful bacterial strains and maintaining optimal ratios of good to bad bacteria. Through probiotic supplementation, large numbers of beneficial bacteria enter the gut, positively affecting health.

Predictably, probiotic supplementation enhances digestive health and can reduce bloating, nausea, constipation, IBS, and other concerns. However, probiotics also reduce inflammation, alleviate allergy symptoms, boost immune health, enhance fat metabolism, and even reduce depression and anxiety while improving cognitive function aspects.

Notably, PROBIO-50 utilizes primarily Lactobacillus and Bifidobacterium strains, which is excellent since these rank among the most extensively researched varieties.

For optimal results, research indicates at least 10 billion CFUs are typically required.

Does PROBIO-50 Work?

After examining the ingredients, PROBIO-50 appears highly likely to function effectively as a gut health supplement. Extensive research supports probiotics generally, and substantial evidence backs CoreBiome and other postbiotics, although much testing has occurred in animals rather than humans.

cutler nutrition probio 50 and total iso

Additionally, both primary ingredients are dosed appropriately, which should yield optimal results.

In essence, PROBIO-50 will likely improve multiple aspects of gut health and overall wellness, given the connection between digestive health and other bodily systems (supported by research). Primarily, PROBIO-50 should reduce inflammation, enhance immune function, and support digestion, but may also benefit energy, cognition, and mental health.

Claims vs. Reality

However, the extent of your benefits may depend on your condition’s severity. While probiotic supplementation benefits healthy individuals with solid microbiomes, the improvements aren’t as dramatic as those experienced by people with various health conditions. This isn’t problematic since most people seeking gut health supplements are already experiencing symptoms and problems.

Another consideration: different strains produce different benefits, and with numerous strains in PROBIO-50, it may not contain the exact combination needed for your specific health concerns. For instance, if you need particular strains for mental health improvement, consuming other strains becomes unnecessary.

While all strains provide benefits, it’s unclear exactly how much of each strain is included and how significantly they’ll affect different health outcomes.

Also, probiotic supplementation requires time to work—don’t expect overnight improvements in immune health, inflammation, energy, or digestion. Probiotic supplementation must be consistent, and you must maintain proper nutrition and healthy lifestyle habits to maximize benefits. After all, you cannot out-supplement poor diet and lifestyle choices (though probiotics may come closest to attempting this feat).

Who is PROBIO-50 Best For?

Considering these factors, PROBIO-50 is ideal for individuals with general health concerns and problems related to poor digestion, inflammation, immune health, and energy levels. This isn’t necessarily for people with severe issues in any specific area, as more targeted supplements would be better suited. However, PROBIO-50 is likely an excellent choice if you’re seeking to improve overall gut health and enjoy the general benefits that follow.

Cutler Nutrition Probio-50 Supplement Bottles

Is PROBIO-50 Safe?

People sometimes become discouraged when probiotics or gut health supplements initially worsen their symptoms, but this typically results from the internal “good vs. bad bacteria” battle. As your body adjusts to the influx of beneficial bacteria, these symptoms will subside and usually improve significantly. Some users may experience no side effects whatsoever. Here are some possible reactions:

  • Temporary increase in gas and bloating
  • Headache
  • Allergic reactions/sensitivities

Additionally, PROBIO-50 is vegan-friendly, non-GMO, gluten-free, and free of fillers and dyes.

Where to Buy PROBIO-50

You can purchase PROBIO-50 by visiting the Cutler Nutrition website at this link.

jay cutler nutrition probio 50 website

Each bottle contains 30 servings (90 capsules). The price for one-time purchase is $49.99 ($1.67/serving), or you can choose the Subscribe and Save option, which reduces the price by 15% to $42.49 ($1.42/serving).

PROBIO-50 is moderately expensive, so consider that daily use is recommended when evaluating the price point.

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PROBIO-50 Review Ratings

  • Ingredient Quality: 4.3
  • Ingredient Dosage: 4.4
  • Effectiveness: 4.0
  • Safety: 4.4
  • Value: 3.5
  • Company Trustworthiness: 4.2

Overall Rating:
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Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.

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