Best Supplements For Inflammation

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By Alexa DaFonte

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

best supplements for inflammation

Inflammation is more than what you may typically think.

It is more than just swelling, and it is actually your body’s response to illness, toxins, trauma, and stress.

Our bodies are naturally able to respond to these internal and external factors to help resolve this inflammation; however, sometimes, we need supplemental help to really reduce that inflammation.

Anti-inflammatory vitamins and supplements vary in their specific roles, but they can greatly help reduce this inflammation in the body and can also help reduce the risk of certain cancers and diseases.

Supplements For Inflammation

Best Supplements For Inflammation

Manna Liposomal Curcumin

Manna Liposomal Curcumin is a liquid curcumin supplement that contains 250mg of curcumin from turmeric root extract.

The star of this product is the liposomal delivery, which is a fancy way of saying that the product is absorbed 10x better than traditional curcumin supplements.

Manna Liposomal Curcumin fights chronic inflammation, relieves joint pain, and support brain health.

The product is made in the USA and backed by a 90-day money-back guarantee.

manna liposomal curcumin

Manna Liposomal Joint Relief

Manna Liposomal Joint Relief is a specialized formula designed to relieve joint pain, stiffness, and inflammation.

This is a great option for people who specifically want to target joint issues. Similar to the company’s Curcumin product, Liposomal Joint Relief contains liposomal curcumin.

The product takes joint relief a step further by including ingredients like glucosamine, chondroitin, MSM, and quercetin.

manna liposomal joint relief


CurcuminMD contains 400mg of Longvida Optimized Curcumin, a form of curcumin that is absorbed 185 times more efficiently than standard turmeric.

The product also contains an herb called boswellia serrata which can help fight joint pain.

This curcumin supplement really helps increase the number of antioxidants in the body and also helps treat minor aches and pains associated with inflammation. This product comes highly rated by users and is one of the more affordable turmeric supplements on the market.

CurcuminMD Plus

Purely Beneficial Resveratrol

Resveratrol is often praised for its anti-aging potential. It provides a powerful source of antioxidants and also helps support your cardiovascular system.

This resveratrol supplement contains 1450 mg of a strong resveratrol blend that contains trans-resveratrol, green tea extract, Vitamin C, acai extract, pomegranate extract, grape seed extract, and blueberry extract.

A 90-day supply only costs about $23, making it a highly rated and affordable product on the market.

Purely Beneficial Reservatrol bottle

Anti-Inflammatory Ingredients

A healthy diet and moderate exercise is the best way to prevent inflammation in the first place. However, there are certain supplements that are often used to help prevent and fight inflammation effectively.

Many of these anti-inflammatory vitamins provide either a source of antioxidants, fatty acids, or a unique compound found in that ingredient. Below are some of the more common anti-inflammatory supplements and their roles in the body.


Ginger is highly inflammatory due to its active ingredients, gingerol, and zingerone, which help fight inflammation. Ginger is typically used to fight gastrointestinal distress (like nausea) and can often help with inflammation related to diabetes and breast cancer. Ginger may also be helpful in treating muscle soreness from exercise.

Curcumin (Turmeric)

Curcumin is the active ingredient in turmeric, which is a spice typically used in dishes like curry.

Curcumin has been studied in more recent years for the treatment of certain cancers. It is also often used to treat and prevent heart disease and diabetes. Many also turn to this supplement for stomach issues as it has been proven helpful for managing symptoms of irritable bowel syndrome (IBS).

It should be noted, though, that to enhance its absorption in the body, you must also consume black pepper alongside it. This is why many turmeric/curcumin supplements also contain pepperine, the active ingredient in black pepper.


Resveratrol is another anti-inflammatory compound typically found in red wine. It is a powerful antioxidant that is often praised for its anti-aging benefits. This compound is especially helpful in reducing the risk of diseases like diabetes and heart disease as it lowers some of these dangerous inflammatory markers in the body (such as inflammatory cytokines).


Zinc is a very powerful antioxidant and anti-inflammatory compound. Many studies prove zinc as being a key player in proper immune health, which is particularly important for older individuals. Many studies have also shown that zinc intake correlates with a lower rate of infection and decreased oxidative stress in the body.

Inflammation Supplement Benefits

Helps The Body Fight Inflammation

Anti-inflammatory supplements help fight inflammation head-on. Taking them continuously can help relieve both immediate and long-term pain/inflammation.

Short-term inflammation is the body’s natural way of protection from things like scratches, cuts, and infections. However, this inflammation can turn into chronic inflammation (especially in the case of diet choices). This long-term chronic pain can show up in the body as arthritis or diabetes, for instance.

Anti-inflammatory supplements can help fight that short-term inflammation and help prevent that long-term, chronic inflammation as well. If you already have chronic inflammation, anti-inflammatory supplements can help relieve some of the pain and associated symptoms.

Helps Prevent Disease

As stated, these supplements help fight inflammation in your body. They can help reduce inflammation right away so as to prevent chronic inflammation that results in disease.

Most anti-inflammatory supplements operate in unique ways, so they may not always provide treatment for the inflammation cure you are looking for.

For instance, omega-3 fatty acids fight vascular inflammation in the body, which helps prevent heart-related diseases.

Curcumin (the active ingredient in turmeric) helps fight inflammation that coincides with diabetes and metabolic issues.

Both zinc and green tea help fight inflammation that occurs as a result of oxidative stress. This helps boost our immune system and keep us healthy as we age.

Why Should I Take Supplements For Inflammation?

Anti-inflammatory supplements can really help fight inflammation in the body. This inflammation may be resulting in immediate pain, so taking a supplement to help fight that inflammation can help reduce the pain you may be feeling.

These inflammation-fighting supplements can also help prevent long-term diseases like cancer, heart disease, and diabetes. Taking some of these supplements (or consuming them in their natural forms) can provide relief from both immediate pains and can help prevent some of these debilitating diseases early on.

Always consult with your doctor before taking any medication/supplement, even if it is supposedly healthy and natural. Anti-inflammatory compounds are usually pretty safe for use, but always do your research and consult a medical professional (especially when it comes to drug interactions).

Do Anti-Inflammatory Supplements Work?

To determine the efficacy of an anti-inflammatory vitamin, you should do some research first. This is because each supplement has a unique role in the body, especially as it pertains to fighting inflammation. For instance, whole omega-3 fatty acids may help fight vascular inflammation (reduces the risk of a heart attack/ heart disease), green tea helps fight oxidative stress and boosts the immune system.

The great thing about these supplements is that they are natural. They are not medications that come with a wide array of side effects, and they usually have many different benefits within the body, so it really can’t hurt to implement them into your routine. Also, consult with your doctor to determine where you may be experiencing inflammation within your body. This can help determine which supplement would work best for you specifically.

Alternatives To Inflammation Supplements

Although anti-inflammatory supplements can be beneficial for your health, they are not necessary. Diet and exercise are very important factors when considering inflammation within the body. For instance, you can take all the anti-inflammatory products you want, but if you’re eating cheeseburgers 4 times a week, the fat build-up can lead to atherosclerosis, plaque build-up, inflammation, and can result in heart disease. Try incorporating more healthy foods in your diet, especially from the plant-based world. Below are some anti-inflammatory foods you can incorporate into your diet.

  • Leafy greens
  • Ginger
  • Spirulina
  • Almonds
  • Walnuts
  • Green tea
  • Tomatoes
  • Olive oil
  • Brown rice
  • Quinoa and other whole grains
  • Fruits in general

Do I Really Need Supplements For Inflammation?

Anti-inflammatory supplements are definitely not necessary for your health, but they also can’t really hurt either. They are not anti-inflammatory medications, so they usually don’t come with a long list of side effects. Many of these supplements come from food sources, though, so consuming these foods may prove cheaper and easier. For instance, try using fresh grated ginger and turmeric in your favorite dishes. You can also consume more leafy vegetables and green tea to help fight inflammation. Consuming a healthy diet is extremely important when dealing with inflammation in the body, so that should always prevail over any supplement. However, if you’re looking to take an anti-inflammatory supplement, consult with a nutritionist or a doctor to find a supplement that would work best for your inflammatory issue.

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Alexa DaFonte

With a degree in Nutrition and Health Sciences from the University of Massachusetts Amherst, Alexa brings a vast knowledge of nutritional sciences, especially as it intersects with modern health and wellness. Due to her passion for a healthy lifestyle, she enjoys spreading awareness of the science behind many of her nutrition practices.