Natural Stacks Serotonin Brain Food Review – Is This Mood Enhancer Effective?

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By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

Natural Stacks Serotonin Brain Food Review

Amidst the stressful, chaotic modern world, it’s safe to say most of us could use a little help with our moods and overall mental health. 

After all, many people are suffering from anxiety, stress, depression, and other mood problems; and this can really put a damper on life. 

However, there are things you can do to improve your mood, including supplementing with the right ingredients.

And in this article, we’ll take a look at a supplement called Natural Stacks Serotonin Brain Food to analyze how effective it is for boosting mood and mental health. 

Keep on reading this Natural Stacks Serotonin Brain Food review if you want to know more about the product, its ingredients, and the possible benefits it has for mood and well-being. 

Natural Stacks Serotonin Brain Food

About Serotonin Brain Food

Serotonin Brain Food is a mood-enhancing supplement created by Natural Stacks. This supplement company is well-known in the health and wellness industry and have produced a variety of other supplements in addition to Serotonin Brain Food, many of which we have also reviewed.

Other Natural Stacks Supplements:

Natural Stacks Supplements

Natural Stacks Serotonin Brain Food is designed to support the body’s natural production of serotonin, which is a key neurotransmitter important for overall mental well-being. 

In fact, many of the common anti-anxiety and anti-depressant medications out there today work to increase levels of serotonin. But they also come with possible side effects, which is why it may be helpful to look for more natural alternatives. 

And serotonin Brain Food contains key precursors and co-factors required for healthy serotonin metabolism, such as l-tryptophan, in addition to other ingredients for general mood support, such as Rhodiola Rosea

And with over 3,000,000+ servings sold and positive customer reviews, Natural Stacks is confident that Serotonin Brain Food will be just what you need for mood.

Natural Stacks Serotonin Brain Food Benefits

The main benefits of Natural Stacks Serotonin Brain Food are:

  • Serotonin Support
  • Better Mood and Well-being
  • Stress Relief
Natural Stacks Serotonin Brain Food Benefits

Serotonin Support

As mentioned, Serotonin Brain Food contains some precursors to serotonin, such as l-tryptophan, designed to support healthier serotonin levels. 

Enhanced Mood and Well-Being

Serotonin Brain Food is also advertised to support/enhance mood and well-being not only by increasing serotonin but also by promoting general mental health with ingredients such as Rhodiola Rosea and magnesium glycinate.

Stress Relief

Serotonin Brain Food is also advertised to offer stress and anxiety relief, with ingredients such as Rhodiola, magnesium glycinate, and l-tryptophan. 

So, will Serotonin Brain Food help users get that much-needed mood boost? Read on to find out!

Serotonin Brain Food Ingredients

The primary ingredients in Serotonin Brain Food are:

  • Vitamin B3
  • Magnesium Glycinate
  • Zinc Glycinate
  • L-Tryptophan
  • Rhodiola Rosea
serotonin brain food ingredients


L-tryptophan (tryptophan) is an essential amino acid that can be obtained from many different food sources, such as nuts, meat, and dairy. 

It is also a precursor to the neurotransmitter serotonin, which is involved in feelings of well-being, mood, sleep, and other functions. 

Current evidence shows that tryptophan supplementation can reduce anxiety and depression while also increasing positive mood. 

Recommended Dose: 500 to 3,000mg

Rhodiola Rosea

Rhodiola Rosea (Rhodiola) is a medicinal herb that grows in colder regions of Europe and Asia. It has a long history of use in traditional medicine and is particularly known for its adaptogenic/stress-reducing properties. 

Rhodiola and its bioactive compounds have been shown to normalize the release of stress hormones while also increasing energy levels. (That’s why it can also be in some nootropic supplements, such as Four Sigmatic Focus). 

Plus, it is able to help sustain or increase neurotransmitters, such as dopamine, serotonin, and norepinephrine. 

And it has been effective for stress and anxiety reduction, decreased burnout, and lessened fatigue. Quite the trifecta!

Recommended Dose: 200 to 600mg

Vitamin B3

Serotonin Brain Food also has a whopping 171mg of vitamin B3, which is over 1,000 percent of the DV.

Vitamin B3 has numerous influences on neuronal health and overall brain function. It helps to reduce oxidative stress and inflammation in the brain, and it is also important for the production of some neurotransmitters, including serotonin.

In fact, vitamin B3 works with tryptophan to help serotonin, so having too little vitamin B3 could lead to decreased serotonin. 

Magnesium Glycinate

Magnesium is a very important mineral involved in hundreds of bodily processes. 

It’s also good that Serotonin Brain Food includes it in glycinate form, which is a chelated form that has a high bioavailability.

Related to the brain/mental health, magnesium is needed for optimal serotonin production, overall neuronal health, protecting the brain from oxidative stress, and for having a healthy stress response.

Low levels of magnesium are associated with decreased serotonin, suicidal tendencies and depression, anxiety, insomnia, and stress.

Fortunately, magnesium, the natural “chill pill,” has been shown to reduce anxiety, depression, and stress. 

You can find it in many other relaxation supplements too, such as Avantera Unwind.

Recommended Dose: 200 to 600mg

Zinc Glycinate

The final ingredient in Serotonin Brain Food is zinc (as zinc glycinate). So, again they use a chelated form, which has a high bioavailability.

Zinc is also a crucial mineral involved in neuronal health and function, brain growth, and neurotransmitter production. 

Deficiencies in zinc are associated with increased depression, anxiety, stress, and impaired cognitive function. 

But supplementing with zinc may help to restore brain function and reduce anxiety, depression, stress, and even irritability. Plus, zinc may help with overall cognitive function too. 

Recommended Dose: 10 to 20mg

Does Natural Stacks Serotonin Brain Food Work?

Natural Stacks Serotonin Brain Food really looks like a solid supplement for mood and mental health. 

Natural Stacks Serotonin Pills

It includes some of the best ingredients for enhancing the production of serotonin and other neurotransmitters. And they’re all well-researched to support mood and reduce anxiety, depression, and stress. 

Plus, most of the ingredients in Serotonin Brain Food are dosed at near perfect amounts, with magnesium glycinate the only ingredient that’s dosed too low. 

Otherwise, tryptophan, Rhodiola, vitamin B3, and zinc are all dosed right within the clinically recommended ranges. 

Claims vs. Reality

In all likelihood, Natural Stacks Serotonin Brain Food should definitely be able to stand by its claims

All of the ingredients in it are proven to support serotonin levels, boost mood and well-being, and reduce stress. 

And since Natural Stacks didn’t make any outlandish claims (such as mood boost by 500% or something like that), users can be confident that they’re getting a trustworthy product.

Keep in mind that Natural Stacks Serotonin Brain Food is likely not a cure-all for your mental health problems, especially if you have more moderate or severe anxiety, stress, depression, etc.

The ingredients in it are most often studied to treat mild cases of mental health problems, so it’s important to be realistic. 

Also, the benefits will likely take a couple of weeks to occur, and likely longer before you reach maximum benefits. 

Who is Natural Stacks Serotonin Brain Food Best For?

Natural Stacks Serotonin Brain Food is best for people looking to support the body’s natural serotonin production and to increase their overall mood while decreasing mild to moderate anxiety, depression, stress, and irritability. Basically, it’s a general mood and emotional support supplement.

Natural Stacks Serotonin Brain Food Bottle

Is Natural Stacks Serotonin Brain Food Safe?

Some possible side effects of Natural Stacks Serotonin Brain Food include:

  • Drowsiness
  • Headache
  • Blurry vision
  • Stomach pain, vomiting, diarrhea, 
  • Difficulty sleeping
  • Dry mouth or excess saliva
  • Flushing

Serotonin Brain Food is made in the USA in a cGMP facility. 

Also, Natural Stacks Serotonin Brain Food is gluten-free, vegan, non-GMO, paleo-friendly, and Open Source certified for full label disclosure. 

How to Take Natural Stacks Serotonin Brain Food

Users are directed to take 2 to 3 capsules of Serotonin Brain Food daily during periods of stress and/or irritability. 

Where to Buy Natural Stacks Serotonin Brain Food

You can buy Serotonin Brain Food on the official Natural Stacks website at this link

serotonin brain food where to buy

Each bottle contains 20 servings (60 capsules). The regular price is $39.95 ($2.00/serving), or you can save 20% by choosing the Subscribe & Save option, which lowers the price to $31.96 ($1.60/serving); you can get it delivered every 1, 2, or 3 months. 

Looking at the price, it is somewhat expensive per serving but certainly still pretty affordable. And this is a fair price given the clinical dosages used in the product, so you should be getting your money’s worth. 

And they also offer a 30-day 100% happiness, money-back guarantee. If you’re not satisfied with Serotonin Brain Food, just let them know, and they’ll refund you; you don’t even have to return the bottle (unless it’s after the first time). 

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Final Verdict: Natural Stacks Serotonin Brain Food Review

Serotonin Brain Food is a really solid supplement with well-researched ingredients known to improve mood and mental health, with pretty much all of the ingredients at solid dosages. That’s why we recommend it as an option for anyone looking to increase serotonin and boost their overall mental/emotional health.

Overall Rating:
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Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.