ProstateMD Review – Is This 1MD Supplement Effective?

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By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

prostatemd review

As a man, prostate health is a very important thing to be aware of, especially as you get older. After all, there’s a reason the dreaded prostate exam is recommended for men 40 years and older, sometimes earlier. So, what can you do to protect your prostate so you can not only have a successful exam but, more importantly, live a healthier life?

Well, supplementation with science-backed products can be a great option alongside a healthy diet and lifestyle. So in this article, we’re going to take a thorough look at one specific prostate supplement called ProstateMD.


In this ProstateMD review, we’ll discuss everything you need to know about this supplement to find out how effective it really is for optimizing prostate health and other functions. Let’s get started!

About ProstateMD

ProstateMD is made by 1MD Nutrition, a company that makes supplements for many different health concerns using science-backed ingredients. Their ProstateMD formula is highlighted by USPlus, which they say is by far the most effective form of saw palmetto extract in existence. Beyond this, there are 10 other ingredients from plant sterols, minerals, and more, all designed to further support the prostate and urinary tract. 

1md products

Overall, ProstateMD is designed to be the purest and most comprehensive male health supplement on the market, having support from Dr. Daniel Brilson, a urologist who says this supplement is the best prostate supplement out there. 

ProstateMD Benefits

The unique formula in ProstateMD is designed to support prostate, bladder, and urinary tract health. Specifically, the benefits of ProstateMD are:

  • Promotes prostate health
  • Supports urinary tract function
  • Supports prostate cell function
  • Helps maintain a normal urination schedule
prostatemd benefits

All of these benefits are attributed not only to USPlus saw palmetto extract, but also to the 10 other ingredients in ProstateMD.  But do these ingredients in ProstateMD actually work? Read on in this ProstateMD review to find out!

ProstateMD Ingredients

ProstateMD is made in capsule form. Below are the ingredients included in each 1-capsule serving of ProstateMD.

prostatemd ingredients

USPLus Saw Palmetto Fruit Extract

Let’s start with their most important ingredient, USPlus, which is a form of saw palmetto extract. Saw palmetto contains various bioactive compounds known to offer anti-androgenic effects in the prostate while also relaxing smooth muscle in the bladder. Respectively, these effects help support prostate health and decrease frequent urination or other bladder difficulties. Saw palmetto also helps to inhibit prostate cell proliferation and increase cell apoptosis which reduces the risk for benign prostatic hyperplasia (BPH) as well as prostate cancer. Lastly, saw palmetto offers anti-inflammatory effects due to its concentration of beta-carotene, lutein, and zeaxanthin, among others. Plus, USPlus is significantly higher in all of these compounds compared to traditional saw palmetto extracts. 

Pumpkin Seed Oil

Pumpkin seed oil is rich in unsaturated fatty acids and phytoestrogens, which are largely responsible for its effects on prostate health. Research shows that pumpkin seed oil decreases androgen levels in the prostate and can protect against abnormal prostate growth. Plus, it offers anti-inflammatory effects and can help relax the bladder. 

Pygeum Bark

Pygeum bark has anti-inflammatory compounds that can inhibit pro-inflammatory prostaglandins in the prostate, thus protecting against BPH. Plus, certain compounds in pygeum bark reduce prolactin levels and reduce cholesterol buildup in the prostate, while also reducing dihydrotestosterone-induced prostate enlargement. 

Lycopene and Lutein

Lycopene and lutein are both carotenoids found in various foods. Both are able to inhibit androgen signaling in both normal and cancerous prostate tissues, showing evidence of both being preventive and restorative compounds. Plus, they have potent antioxidant effects. 

Monterey Pine Bark Extract

Pine bark extract is known for its antioxidant profile, which has benefits on the prostate and overall urinary tract health. Research has shown that pine bark extract supplementation helps decrease BPH and leads to improvements in bladder volume, bladder emptying, urination frequency, nighttime urination, and weak flow, among other urination-related problems. 

Stinging Nettle Leaf

Stinging nettle leaf is rich in fatty acids, sterols, and flavonoids that may protect against BPH. Current research shows that stinging nettle is effective for reducing prostate volume, improving urine flow, and reducing the risk of prostate cancer, likely due to its antioxidant and androgen-inhibiting effects. 

Sunflower Seed Lecithin

Sunflower seed lecithin is primarily included to enhance the absorption of the other ingredients, such as lycopene and lutein. It may also have some of its own benefits too, such as antioxidant effects. 

Safflower Seed Oil

Safflower seed oil is rich in phytoestrogens which can help to decrease testosterone and DHT in the prostate, thus protecting against BPH and prostate cancer. 

Boron and Copper

Finally, we have boron and copper, two trace minerals. Both of these have been shown in research to inhibit prostate cancer cell proliferation and can even kill prostate cancer cells, while keeping healthy prostate cells intact. Plus, they can reduce prostate-specific antigen levels.

Does ProstateMD Work?

ProstateMD appears to be a high-quality prostate support supplement. The ingredient they talk most about, USPlus saw palmetto, definitely has research behind it showing it can reduce BPH and improve overall prostate health. And the other ingredients are also well-researched and seem to be effective for decreasing prostate size, reducing the risk for BPH and prostate cancer, improving urination, and supporting overall bladder and urinary tract health.  These ingredients mainly decrease androgen actions in the prostate while also inhibiting cancer cell growth and providing anti-inflammatory and antioxidant effects. And it is these actions that make ProstateMD a solid supplement. 

prostatemd male health supplement

Claims vs. Reality

Since most of the claims made by 1MD Nutrition for ProstateMD are general, they can be stood by. After all, the research shows ProstateMD should be able to improve prostate, bladder, and urinary tract health, as they claim.  The makers of ProstateMD also note an expected timeline of benefits, in which the best effects aren’t seen until about 90 days of use. So, it’s important to take this product consistently and for a long time, and to not expect anything major right away. 

1md product box

Who is ProstateMD Best For?

ProstateMD is best for any man looking to optimize their prostate health and reduce the complications that come with an enlarged prostate, such as nighttime urination, frequent urination, discomfort, pain, and so forth.  Older men are more likely to benefit simply because they’re more likely to have these issues. It can also be used to protect against BPH or prostate cancer, but always consult your doctor first. Also, remember that this isn’t designed to treat, prevent, or cure any disease. 

prostatemd designed for men

Is ProstateMD Safe?

ProstateMD is generally recognized as safe, but below are some potential side effects:

  • Headaches or dizziness
  • Nausea, vomiting, diarrhea, or constipation
  • Sexual problems, such as ejaculation difficulties and erectile dysfunction

ProstateMD is manufactured in the USA in an FDA-regulated using GMP standards. It is also non-GMO and free from shellfish, dairy, peanuts, and wheat. 

Where to Buy ProstateMD

You can buy ProstateMD on the official 1MD Nutrition website here. Each bottle contains 30 servings (30 soft gels). You can buy 1,3, or 6 bottles at a time, either as a one-time purchase or through their Subscribe and Save option. That means there are 6 different pricing options.

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Below, we will detail the regular pricing as well as the subscribe & save pricing for ProstateMD. ProstateMD Pricing:

Additionally, you’ll get free shipping on the 3-bottle and 6-bottle options. ProstateMD Subscribe & Save Pricing:

With the subscribe & save option, you’ll get free shipping on all orders, can cancel at any time, and receive out-of-stock protection. So, the price range for ProstateMD is anywhere from $1.20 to $1.67 per serving. This is a moderately expensive product, so if you find that it works for you, definitely consider going with the bulk and/or Subscribe and Save options. 

More reviews of 1MD products:

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Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.