GutMD Review – Does This 1MD Gut Health Supplement Work?

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By Leslie Waterson

Reviewed by Juliana Tamayo, MS, RDN - Last Updated


Gut health plays a crucial role in our overall health. Yet, many of us do not think too much about it because we think, reasonably, that gut health is only about our stomachs and digestive health issues.

However, gut health goes beyond our stomach and digestive health issues – it affects different areas such as weight, sleep, mood, skin health, and some more. Simply put, a healthy gut will positively affect these areas, while an unhealthy gut can cause negative effects on them. Therefore, taking care of your gut should be one of your top priorities.

Aside from living a healthy lifestyle, taking dietary supplements is one of the ways to take care of your gut. In this article, we have GutMD by 1MD.

As the name suggests, GutMD is basically designed to promote overall gut health. But will it stand up to its role? Is it a promising supplement, or it’s just all hype? In this review, we are going to review what GutMD is, and more importantly, if it is a potentially effective supplement.

 We will dive into the following in the rest of this review: 

  • Details about GutMD
  • Review the pros and cons of its ingredients 
  • Discuss consumer’s reviews
  • Share where you can purchase the product
  • Provide pricing details of GutMD
  • Give our review out of 5 stars

Let’s jump right into it with this GutMD review!


About GutMD

GutMD is a gut health supplement made by 1MD, a supplements company that produces dietary supplements to address the different needs and issues of our health. 1MD has an extensive supplement line with products including OsteoMD, GlucoseMD, ImmunityMD, and many others.

GutMD is 1MD’s answer to your gut health needs. As a gut health supplement, here are some of the benefits that you can get from GutMD as described by its product description:

  • Support gut lining integrity
  • Boosts immune system function
  • Protects gut from harmful bacteria
  • Support for overall gut and digestive health

Regarding allergens and artificial ingredients, GutMD is free from gluten, soy, and shellfish. It is also free from any preservatives. However, GutMD contains milk, which may not work well if you are lactose-intolerant.


Now that we got to know the basics about GutMD, let’s now see if this supplement is promising or not. To do that, let’s check the label to see what we are getting from it – that is, its ingredients!

GutMD Ingredients

GutMD contains 4 main ingredients. They are:

  • Acacia Fibregum
  • L-Glutamine
  • GutGard
GutMD® supplement facts

Acacia Fibregum

Acacia fibre gum is a type of dietary fiber. As a fiber, acacia fibre gum acts as a prebiotic (food for your probiotics) to your probiotics (healthy bacteria that work for your gut). Acacia fiber is also different compared to your typical fiber in a way where it ferments slower compared to a regular fiber. While all fiber is meant to be digested slowly, acacia fiber is fermented and digested more slowly than it can survive its way until it reaches the very bottom of your colon. This makes it capable of spreading prebiotic benefits throughout your digestive system.

Aside from gut health benefits, acacia fibre gum is also known to be beneficial for high cholesterol and is helpful in treating diabetes.


HMO CARE4U is a human identical oligosaccharide (HMOs) that are made from natural ingredients and are used to mimic the benefits of natural HMOs found in breast milk. HMOs are prebiotics that can only be found in breast milk. HMOs are very crucial for the development of an infant, especially the infant’s immune system. This is achieved by feeding the infant healthy bacteria with oligosaccharides.

The goal of HiMOs such as GutMD ‘s HMO CARE4U is to mimic such benefits by natural HMOs. However, there aren’t a lot of studies so far showing how effective HiMOs are and if they really have benefits, to begin with. As for HMO CARE4U, it’s only produced in one lab, and therefore, more research is needed before we can conclude that the said HiMOs have proven benefits and are effective.

To be clear, we are not saying that HMO CARE4U (and HiMOs in general) is ineffective. However, the supposed benefits of HiMOs are so far mainly based on theory and thought rather than on solid research. While HiMOs should logically mimic the benefits of HMOs, we still need research-based evidence that shows that HiMOs indeed provide benefits and mimic their natural counterparts.


L-glutamine is a type of amino acid that plays a vital function in our immune system. Specifically, l-glutamine (and glutamine in general) act as a rich fuel source for your immune cells, including those that are found in your intestines. This, in turn, sustains and supports your overall immune system.

Aside from providing benefits to our immune system, l-glutamine also specifically supports our gut health as well. Specifically, l-glutamine strengthens and reinforces the gut barrier, which separates your intestines and the rest of your body. This will protect your bloodstream from potential leakage from your intestine (leaky gut), which could cause mild to serious harm if it happened otherwise.


GutGard is a special ingredient that was derived from the licorice root. Its main role is to protect our gut from harmful bacteria, which causes a reduction in nutrient absorption.

In general, licorice root contains antiviral, antitumor, antimicrobial, and anti-inflammatory properties, making it very beneficial both for your gut and overall health. Regarding gut health, licorice root is said to have health benefits such as ulcers and stomach pains. Other health benefits associated with licorice root include fighting off skin inflammation and helping our respiratory system to function properly by increasing the production of healthy mucus.


GutMD Benefits

So far, what I like the most about GutMD is both the simplicity and potency of its ingredients. With the exception of HMO CARE4U, which still awaits more research to confirm (or disconfirm) its effects and benefits, GutMD’s ingredients are simply potent. The formulation of GutMD is also simple but promising nevertheless.

Like other 1MD products, GutMD also offers a 90-day money-back guarantee. This is also great, especially if you are cautious when spending on a new supplement, which is very understandable! But at the same time, having a 90-day money-back guarantee means that the company really trusts their product and that they’re even willing to risk potential refunds.


Is GutMD Safe?

As a gut health or gut-related supplement, GutMD could potentially cause minor side effects in the gut, such as diarrhea and constipation. This can especially happen if you took too much of the supplement than what is recommended or if the formulation happens to be too much for your body. True enough, a few reviews report that GutMD caused side effects such as constipation.

Other than that, there are no known side effects related to GutMD. Still, you should consult your doctor before trying the supplement, especially if you are pregnant, nursing or if you are currently taking medications.

Aside from side effects, you should note that, as mentioned earlier, GutMD is not good if you are lactose-intolerant as the supplement contains lactose (milk). But other than that, you should probably be fine as the supplement is gluten-free, soy-free, and shellfish-free.

Is GutMD Worth A Try?

Overall, GutMD is a promising supplement that can promote gut health – and in this case, even immune health and just overall health. Again, I like the fact that GutMD is both simple and potent. So, overall, I would say that the supplement is worth trying out!

If you are worried about the product, GutMD offers a 90-day money-back guarantee. So, if it didn’t work for you, you can get your money back.

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Where To Buy GutMD

If you want to check out GutMD, you can buy it on the Gundry MD website, here. One bottle is normally $49.99, but right now you can get 16% off bringing one bottle to $41.99. If you really like GutMD, though, you can save even more by stocking up. You can get 3 bottles for $37.99 each ($36 savings) or 6 bottles for $33.99 each ($96 savings).

They offer a 90-day money-back guarantee which is pretty great.

GutMD® where to buy

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