Best Anti-Inflammatory Supplements – 5 Top Picks

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By Alexa DaFonte

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

Best Anti-Inflammatory Supplements

Inflammation is commonly thought of through external bodily reactions, like acne and swollen joints/muscles. However, internally, inflammation in the body can lead to a plethora of diseases and ailments, including cancer, heart disease, a weakened immune system, diabetes, and arthritis. Reducing inflammation in the body, and preventing it in the first place, can be initiated through a healthy diet and the introduction of some research-proven supplements.

What Are Anti-Inflammatory Supplements?

Anti-inflammatory supplements are supplements that reduce inflammation and oxidative stress in the body. They can help heal and prevent inflammation resulting from ailments like heart disease, diabetes, arthritis, IBS, and cancer. Inflammation in the body can sometimes trigger other diseases and ailments as well, so reducing overall internal inflammation is essential, and there are quite a few supplements and food sources that are capable of doing just that.

Best Anti-Inflammatory Supplements

Some of the most common anti-inflammatory supplements include turmeric (curcumin), fish oil, resveratrol (the compound found in berries), ginger, and CBD (cannabidiol, the active compound found in cannabis). Many food sources, like grapes, apples, and different berries, are packed with antioxidants and are highly anti-inflammatory.

Benefits Of Taking Anti-Inflammatory Supplements

Anti-inflammatory supplements can help ease the symptoms associated with certain diseases like heart disease, cancer, acne, and arthritis; however, they can also help ward off inflammation in the first place. Inflammation in the body leads to a lot of various diseases and can trigger this cascading effect of varying ailments. Inflammation is commonly triggered by diet and lifestyle factors, so remedying those issues is crucial.

With a healthy diet rich in antioxidants, these varying diseases can be healed and also prevented. The following diseases have been shown to be mitigated with these changes:

  • Acne
  • Heart disease
  • Cancer
  • Atherosclerosis
  • IBS
  • Alzheimer’s Disease
  • Obesity
  • Constipation
  • Diabetes
  • Arthritis

Different Forms Of Anti-Inflammatory Supplements

Anti-inflammatory supplements come in capsules or tinctures. Most supplements are more concentrated than their food counterpart; however, eating foods rich in antioxidants and anti-inflammatory compounds proves beneficial as well. Things like berries, fish, ginger, and turmeric (mixed with black pepper) are great anti-inflammatory and antioxidant sources that should be implemented into the diet.

Different Forms of Anti-Inflammatory Supplements

Do Anti-Inflammatory Supplements Actually Work?

Research has shown the efficacy of anti-inflammatory supplements and antioxidants in the diet. For example, research has shown that turmeric blocks the molecule NF-kB that can activate inflammation within cells, thus showing how turmeric really does shut down inflammation within the body.

Another study proved that fish oil increases the amount of anti-inflammatory molecules in the blood. Higher concentrations of these supplements are often necessary to bring about drastic benefits like these, so that is why supplemental forms of these compounds are often recommended.

Are Anti-Inflammatory Supplements Right For Me?

Anti-inflammatory supplements are not just for those individuals with inflammatory diseases. Although these supplements can help manage diseases like arthritis, cancer, and digestive disorders, they are also great for preventative health. Taking care of our bodies, especially in terms of warding off certain diseases, means preventing inflammation in the first place.

Inflammation tends to spread within the body, so keeping any type of inflammation at bay is essential. Dietary changes to cut out inflammation from certain plaque-building foods are essential, but certain supplements can also be helpful. As with any supplement, it is important to consult a doctor first, but many of these are derived from food sources, so even incorporating these foods into your diet can prove beneficial.

Best Anti-Inflammatory Supplements

CurcuminMD Plus

CurcuminMD Plus Supplement

Our number one pick for best anti-inflammatory supplement is CurcuminMD Plus from 1MD. This supplement is 285x more absorbable than standard, usual turmeric and is designed to relieve sore joints, support heart health, provide antioxidant effects, and promote a cognitive boost. Its formula includes the two main ingredients of Longvida Optimized Curcumin Extract and 65% Standardized Boswellia Serrata Extract with the additions of maltodextrin, sunflower lecithin, and stearic acid. CurcuminMD Plus is also gluten-free, soy-free, non-dairy, and non-GMO as well as vegan-friendly.


Bulletproof Curcumin Max


Our top choice for anti-inflammatory supplements is Bulletproof Curcumin Max. Bulletproof is a well-known supplement company that produces a wide variety of products, including Bulletproof Collagen Protein and Bulletproof Brain Octane Oil. Bulletproof Curcumin Max is a curcumin supplement that provides whole-body support. It contains a clinically-backed turmeric and curcumin complex, as well as ginger, Stephanie, and boswellia. This supplement provides benefits such as supporting recovery after exercise, supporting a healthy inflammation response, and supporting joints and mobility.


OmegaWell by LiveConscious

Live Conscious OmegaWell

OmegaWell offers 2,000mg of fish oil in softgel form. It’s sustainably sourced and maintains a high grade of oil freshness. The product is made in the USA and third party tested for quality. The company also provides a 365 day money back guarantee.


Nature’s Way Premium Ginger Root


Ginger is highly anti-inflammatory, especially when it comes to inflammation within the digestive system. This product helps target digestive issues and promotes joint health. This supplement is non-GMO, contains 1.1 grams of ginger per serving, and comes highly-ranked by customers even at its affordable price.


Alternatives To Taking Anti-Inflammatory Supplements

As supplements can often be a bit costly, eating an anti-inflammatory diet can also prove to be effective in reducing inflammation in the body. Consuming a diet rich in various fruits and vegetables can be very beneficial. Berries are a great source of antioxidants known as anthocyanins. Other antioxidant-rich foods include broccoli, avocados, green tea, cacao, and green tea.

alternative for Anti-Inflammatory Supplements

Turmeric is also a great spice you should incorporate into your diet. Turmeric can be found in many supplements, such as PuraTHRIVE and Protandim Nrf2 Synergizer. The active ingredient in turmeric, curcumin, is highly anti-inflammatory. It is most readily absorbed and effective when combined with black pepper (pepperine), though, so always incorporate those two together. However, research does show that the amount of curcumin needed to be very effective is quite large, so curcumin in supplement form is most effective. Turmeric certainly can’t hurt in your diet, though.

Anti-Inflammatory Supplement Take-Aways

Overall, implementing anti-inflammatory supplements and antioxidants into your diet and lifestyle proves extremely beneficial. Whether you are suffering from an ailment or not, reducing inflammation in the body is essential. Inflammation tends to trigger many different diseases and symptoms externally and internally, so reducing the level of bodily inflammation and oxidative stress is essential.

Although many supplements provide concentrated levels of beneficial compounds, consuming a diet rich in berries, healthy omega-3 fatty acids, and spices like turmeric can largely reduce and prevent inflammation in your body.

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Alexa DaFonte

With a degree in Nutrition and Health Sciences from the University of Massachusetts Amherst, Alexa brings a vast knowledge of nutritional sciences, especially as it intersects with modern health and wellness. Due to her passion for a healthy lifestyle, she enjoys spreading awareness of the science behind many of her nutrition practices.