Primal Gut Restore Review – Does This Primal Harvest Supplement Really Work?

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By Meghan Stoops, RDN

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

Primal Gut Restore Review

Scientists and consumers alike are starting to realize the importance of gut health in many different aspects of our lives. That’s why gut health supplements have become so prominent.

The issue is, with so many different supplements on the market touting exotic claims, it can be challenging to find a high-quality, well-rounded gut health supplement that is researched-backed. Not to mention, no one wants to be taking a myriad of pills each morning.

Because of all these reasons, many people are starting to look at Primal Harvest’s Primal Gut Restore.

With probiotics, prebiotics, and postbiotics in 2 tiny capsules a day, this supplement seems too good to be true. But is it? Keep reading our Primal Gut Restore review to find out!

Primal Gut Restore

About Primal Gut Restore

Marketed as the ultimate gut restore product, Primal Harvest’s Primal Gut Restore is a prebiotic, probiotic, and postbiotic supplement all wrapped in one.

The supplement contains B. longum BB536 for digestion and regularity and CoreBiome Tributyrin for a strong gut barrier. These ingredients serve as the foundation for the complete gut health formula (more on this later). 

First, let’s take a look at the company behind the supplement.

Founded in 2018 by Dan Harper in Farmingdale, New York, Primal Harvest boasts “complete ingredient transparency” in their products. Their website claims their supplement ingredients are based on scientific research and standardized clinical studies.

In addition to Primal Gut Restore, Primal Harvest has produced a wide variety of supplements, including Primal Flex, Primal Greens, Primal Harvest Multivitamin, and Primal Harvest Collagen. All Primal Harvest products are made in the United States and are Good Manufacturing Practices (GMP) certified in Food and Drug Administration (FDA) approved facilities. 

Primal Gut Restore And Other Primal Supplements

Primal Harvest markets a holistic philosophy, encouraging supplements over pharmaceuticals as a way of aiding in and maintaining health. 

Primal Gut Restore Benefits: Prebiotics, Probiotics, and Postbiotics


Our digestive system contains a vast number of microbes that function to maintain our health. Prebiotics are nutrients broken down and selectively fermented by probiotics, sometimes referred to as probiotic’s food, which assists in creating a healthy colony of bacteria in our gut [1]. 

Food sources of prebiotics are primarily classified as soluble fibers and can be found in foods such as soybeans, inulin (which is found in bananas and Jerusalem artichokes), jicama and chicory root, raw oats, unrefined wheat and barley, garlic, onions, and cooked whole wheat flour [1]. 

Prebiotics provide a plethora of benefits. Prebiotics are believed to inhibiting certain strains of bad bacteria and preventing diarrhea. Prebiotics are also believed to provide numerous health benefits such as anti-cancer and anti-allergic effects, increased mineral absorption, and many others that continue to be studied. Further research remains warranted on their health effects in supplement form with human trials [1].

Prebiotic-Rich Foods

  • Chicory root
  • Dandelion greens
  • Jerusalem artichokes
  • Garlic
  • Onion
  • Leeks
  • Asparagus
  • Barley
  • Bananas


The microbes in our digestive system consist of bacteria, fungi, and other microorganisms known as probiotics. In a healthy person, probiotics would exert positive functions such as aiding in metabolism and protecting us from pathogenic organisms.

Evidence shows probiotics can potentially help to prevent and/or treat certain conditions, including bowel disorders, such as diarrhea (antibiotic-associated and infectious), irritable bowel syndrome, inflammatory bowel disease, lactose intolerance, allergy symptoms, immunity, hepatic encephalopathy, and even dry mouth [1, 2].

With a wide spectrum of potential health benefits, probiotics are still being extensively studied for their use in human health. Despite significant evidence in their favor, probiotics remain controversial due to the limited research available on their mechanism of action. With a vast variety of different strains that all appear to function differently in the gut, further research is needed to fully understand their role and how we can best utilize them for health purposes [2].

Probiotic-Rich Foods

  • Fermented dairy products such as yogurt or kefir
  • Other fermented foods such as pickles, kimchi, sauerkraut, miso, and tempeh


Postbiotics is a relatively new term in the science world; however, researchers have been studying postbiotics and their potential health effects for numerous years. Postbiotics are the result of probiotics feeding on prebiotics. In a healthy gut, the body would produce Tributyrin, a microbial metabolite that is now being marketed as a functional food or supplement on its own [3]. 

Postbiotics are still being extensively researched for their role in human health. Current research shows potential benefits including anti-inflammatory, immunomodulatory, antioxidant, and anti-obesogenic properties, ability to help lower blood pressure and cholesterol levels, and reduce cancer risk by inhibiting tumor growth [4].

Primal Gut Restore Pill Capsules

Does Primal Gut Restore Work?

Many consumers reported decreased digestive concerns and smoother digestion, increased energy, improved mood, skin, and general wellbeing. With 4.9 out of 5-star reviews on their website, it appears many Primal Harvest consumers feel this supplement is a beneficial addition to their health regimen.

Claims vs. Reality

Primal Harvest’s Primal Gut Restore claims to support gut health, natural immune responses, and energy levels. Numerous research studies conducted on prebiotics, probiotics, and postbiotics favor these claims; however, there is further research needed on these supplements and their potential benefits and safety of use.  

Primal Gut Restore Ingredients

Primal Harvest Primal Gut Restore is a gluten, dairy, and soy-free, USA-made supplement. Primal Gut Restore’s ingredients include prebiotic xylooligosaccharides, probiotic B. Longum, BB536, and postbiotic CoreBiome Tributyrin. 

Primal Gut Restore Bottle And Pills

Xylooligosaccharides Prebiotics

Primal Gut Restore contains 100mg of the prebiotics xylooligosaccharides, a type of non-digestible fiber that helps to stimulate prebiotic Bifidobacterium and other lactic acid bacteria in the gut and is believed to provide a plethora of health benefits. 

Claimed by Primal Harvest to help ward off cravings and help you feel full longer, xylooligosaccharides act as most fibers in the role of satiety. Considered a functional fiber along with a prebiotic, xylooligosaccharides have also been shown in some research studies to exert anti-inflammatory, antioxidant, and anti-allergy effects that are believed to improve immunity, decrease cancer risk, and lower cholesterol levels [5,6].

B. Longum BB536 Probiotics

Primal Gut Restore contains 3 billion CFU of the probiotic Bifidobacterium Longum BB536 for digestion and regularity. This probiotic strain is known to be more stable with a longer shelf life than other probiotic strains. 

Clinically effective and well-established, this probiotic strain is a multifunctional probiotic shown to exert many positive effects on human health. B. Longum BB536 has been used to help alleviate digestive, immunological, and infectious diseases. Despite strong clinical evidence, the mechanism of action for these probiotics continues to remain unclear, and further research is warranted [7].

CoreBiome Tributyrin Supplement

Primal Gut Restore contains 1000mg of postbiotic Tributyrin. Tributyrin is naturally produced by healthy bacteria in the gut. Claimed #1 post-biotic in the world, CoreBiome claims to help strengthen the gut barrier

Created by Compound Solutions with patent-pending, CoreBiome is short-chain fatty acids (SCFA) naturally produced by a healthy gut that are believed to help probiotics thrive. Most research studies are conducted on mice or piglets; more studies are needed for human trials [3,4].

Is Primal Gut Restore Safe?

Side effects reported were limited and mild in nature, including upset stomach, diarrhea, gas, and bloating.

Probiotic B. longum BB536 is generally recognized as safe (GRAS) by the FDA because these microbes naturally exist in our body. Prebiotic Xylooligosaccharides are also on the FDA GRAS list as these are commonly found in many food sources, as well as Tributyrin postbiotics if GMP are followed. 

These supplements are not recommended or should be used with caution for those who have a weak or compromised immune system which can put you at risk for developing illness.

Who is Primal Gut Restore Best For?

Those looking to improve gut health or who suffer from digestive ailments such as irritable bowel syndrome, inflammatory bowel disease, or Crohn’s disease might benefit from this supplement. 

Those who struggle with getting pre and probiotics in their diet might also benefit from Primal Gut Restore.

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Where to Buy Primal Gut Restore

Primal Gut Restore is available directly from the official Primal Harvest website here. They offer 3 options for order size with prices decreasing the more you buy. Below we will detail the pricing and discounts available for Primal Gut Restore.

Primal Gut Restore Pricing:

Primal Harvest Primal Gut Restore Website

Unfortunately, this product is only available online on the Primal Harvest website, and some consumers have complained it is frequently out of stock or sold out.

More reviews of Primal Harvest products:

Overall Rating:
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Meghan Stoops, RDN

Meghan Stoops is a Registered Dietitian and licensed Nutritionist with a bachelor’s in Dietetics from San Diego State University. Meghan developed an interest in dietetics early on through her own personal struggles with nutrition misinformation. She began doing her own research, which sparked her passion for nutrition and it’s impact on our physical and mental health. Today, she takes take a non-diet, all-foods-fit approach to nutrition, and is devoted to teaching others that eating healthy does not mean restriction or sacrifice.

  • [1] Jain, Monika, Khushboo Gupta, and Payal Jain. "Significance of probiotics and prebiotics in health and nutrition." Malaya Journal of Biosciences 1.3 (2014): 181-195.
  • [2] Kechagia, Maria et al. “Health benefits of probiotics: a review.” ISRN nutrition vol. 2013 481651. 2 Jan. 2013, doi:10.5402/2013/481651
  • [3] Vrzáčková, Nikola et al. “Postbiotics, Metabolic Signaling, and Cancer.” Molecules (Basel, Switzerland) vol. 26,6 1528. 11 Mar. 2021, doi:10.3390/molecules26061528
  • [4] Aguilar-Toalá JE, Garcia-Varela R, Garcia HS, et al. Postbiotics: an evolving term within the functional foods field. Trends Food Sci Tech. 2018;75:105-114.
  • [5] Jain, Ira et al. “Xylooligosaccharides: an economical prebiotic from agroresidues and their health benefits.” Indian journal of experimental biology vol. 53,3 (2015): 131-42.
  • [6] Aachary, Ayyappan Appukuttan, and Siddalingaiya Gurudutt Prapulla. "Xylooligosaccharides (XOS) as an emerging prebiotic: microbial synthesis, utilization, structural characterization, bioactive properties, and applications." Comprehensive Reviews in Food Science and Food Safety 10.1 (2011): 2-16.
  • [7] Wong, Chyn Boon, Toshitaka Odamaki, and Jin-zhong Xiao. "Beneficial effects of Bifidobacterium longum subsp. longum BB536 on human health: Modulation of gut microbiome as the principal action." Journal of functional foods 54 (2019): 506-519.