EstroOne Review – Does This NutraOne Estrogen Blocker Really Work?

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By Alexa DaFonte

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

EstroOne Review

About EstroOne

EstroOne is an estrogen blocker product that is intended for use by men. It supports healthy estrogen and testosterone levels in men and has many health benefits, especially within the fitness and weight loss realm. This hormone regulating product also helps eliminate estrogen rebounding, reduces water retention, and promotes overall fat and weight loss. It can also help optimize muscle building and growth. This product is a hormone-regulating product, which is always very risky as hormonal imbalances can affect the entire body. Let’s take a closer look at this supplement to see if it’s actually helpful in this review of EstroOne.


EstroOne Benefits

Aids In Weight Loss

This estrogen reducing and blocking supplement helps detoxify xenoestrogen from the body. These xenoestrogens are a type of hormone that specifically mimic estrogen’s role in the body. Reducing these levels may help reduce body fat as well as water retention, which may result in weight loss. Regulating estrogen levels may also be beneficial for weight loss as abnormal hormone levels in the body causes water and weight retention and may be impeding your ability to lose weight effectively.

Promotes Muscle Building

By reducing and balancing estrogen levels in the body, this supplement also provides support for healthy testosterone levels. This may help increase muscle density and promote the growth of muscle, especially for males looking to bulk up from gym exercises. Reducing estrogen levels can also help improve both drive and mood.

Eliminates Estrogen Rebound & Promotes Healthy Estrogen Levels

EstroOne primarily works to reduce and restore healthy estrogen levels in the body. This can help offset and eliminate any sort of estrogen rebounding that may occur in the body. This hormone regulating product can also help promote the healthy metabolism of estrogen in the body. Overall, this product is basically an estrogen blocker used for weight loss and muscle gain (by males).


EstroOne Ingredients

The proprietary blend in EstroOne includes a few different ingredients. The first ingredient is white button mushroom extract in a 10:1 ratio. This extract has been proven by some research studies to effectively block aromatase activity. Aromatase is directly involved in the synthesis of estrogen, so by blocking it, estrogen production decreases.

Another ingredient in the formula is diindolylmethane (DIM). DIM increases the “good” estrogen metabolites, which helps reduce “bad” estrogen levels in the body. The “good” estrogen metabolites promote a slightly higher testosterone level in the body as well. These hormone levels increase your metabolism and help you burn fat more effectively as well.

Indole-3-Carbinol is another ingredient included in the formula. This compound actually converts to DIM in the body and effectively helps block estrogen levels in the body as well. This is also used to lower signs of cancer by preventing the development of estrogen-related cancers.

The other ingredient is Acacetin. This compound has been proven to help with weight loss and is often associated with a reduction in estrogen synthesis. This is a powerful estrogen blocker.


Is EstroOne Really Healthy?

EstroOne is healthy in that it includes scientifically proven ingredients in its formula. These ingredients are used in many hormone-regulating products and supplements. Also, many of the ingredients in this formula are phytochemicals, meaning they originate from plants and can be found in different vegetables.

However, this is a hormone-regulating supplement which has its own associated risks. Regardless of your gender, when you adjust and attempt to regulate your hormone levels through supplements, there are some risks. Your estrogen and testosterone levels regulate so many different aspects of your body, ranging from your skin to your risk for developing certain cancers. You should always consult with your doctor before taking a hormone regulating supplement, even if it is just intended to promote weight loss.

Who Should Use EstroOne?


EstroOne seems to be a product targeted towards males, and many other sites openly market this product as a male-only supplement. This is because this supplement blocks estrogen and consequently increases testosterone levels. This would be problematic for females who depend on healthy estrogen levels and production for fertility and menstrual cycle reasons. However, even if you are a male, you should consult with your doctor before taking this supplement.

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Is EstroOne Safe?

This product might have some consequences and associated side effects as it directly regulates your hormone levels. The following are some side effects associated with estrogen blockers:

  • Headaches
  • Insomnia
  • Erectile dysfunction
  • Flushing
  • Feeling tired
  • Weakness
  • Body aches and pains
  • Thinning hair
  • Weight changes

Many of these estrogen blockers are not approved by the FDA, and although there is some research in this area, it is very important to consult with a medical professional before taking a hormone-regulating compound.

EstroOne Alternatives

There are some natural alternatives to estrogen blockers that have also been proven to be effective (and might even have fewer side effects). The following are some natural estrogen blockers:

  • Maca (This is a cruciferous plant that helps block estrogen production in males)
  • Grape seed extract (this acts as an aromatase inhibitor or estrogen blocker)
  • Wild nettle root (nettles contain chemicals that naturally block estrogen production)
  • Cruciferous vegetables (these are natural plant-based sources of DIM)

Where To Buy EstroOne


EstroOne is available directly from the NutraOne website as well as form the 5 Star Nutrition website. It is also available from Amazon. The price is roughly $39.99.

Overall Rating:
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Alexa DaFonte

With a degree in Nutrition and Health Sciences from the University of Massachusetts Amherst, Alexa brings a vast knowledge of nutritional sciences, especially as it intersects with modern health and wellness. Due to her passion for a healthy lifestyle, she enjoys spreading awareness of the science behind many of her nutrition practices.