Best Hyaluronic Acid Supplements – 5 Top Choices

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By Leslie Waterson

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

Best Hyaluronic Acid Supplements

One of the key components in maintaining smooth skin, skin glow, and hydration is hyaluronic acid (HA). Although it has gained popularity for treating skin problems as a serum, it also can be taken in capsule form to help a variety of body ailments.

Hyaluronic acid naturally occurs in our body as a clear substance in our skin, eyes, and connective tissues. As we age, the amount of hyaluronic acid in our body starts to naturally decrease. Because of its continuous decrease, it is important to take hyaluronic acid in external forms such as supplements. If we want to retain the optimal benefits it gives to our skin and overall physical health, taking it in capsule form is suggested.

Below, we will discuss what hyaluronic acid is, its health benefits, how to take it properly, and our picks for the best hyaluronic acid supplements.

Best Hyaluronic Acid Supplements

What Is Hyaluronic Acid?

Hyaluronic acid (HA) is a sugar compound that naturally occurs in our body, specifically in our skin. Its main purpose is to keep the skin hydrated and maintain its glow. One significant role that hyaluronic acid plays is that not only does it hold the moisture of our skin and joints, but it also prevents the same moisture from evaporating into the air. In short, hyaluronic acid works to keep the moisture levels of our skin and joints adequate.

Over time, hyaluronic acid naturally decreases as we grow old, so it is important to sustain ourselves using external sources such as supplements if we want to keep receiving the benefits of hyaluronic acid.

Hyaluronic Acid

Hyaluronic Acid Supplement Benefits

One of the most common uses of hyaluronic acid is the treatment and management of osteoarthritis, also known as “wear-and-tear arthritis”. Research shows that the oral supplement can offer similar benefits to hyaluronic acid injections or facial hyaluronic acid serums.

Hyaluronic Acid for arthritis

While its best known for its impact on treating osteoarthritis, hyaluronic acid can also show more health benefits and treatments other than just treating osteoarthritis. Here are some other health benefits one can get if he or she receives a sufficient amount of hyaluronic acid.

1) Hyaluronic Acid Can Promote Healthier Skin

One of the main benefits of hyaluronic acid is its ability to promote more supple, healthier, and glowing skin. In fact, as mentioned above, hyaluronic acid is naturally produced by our body to perform that function, and maintain a youthful appearance.

Hyaluronic acid that is present in your skin binds water to retain as much moisture as possible. At the same time, it helps in preventing that moisture from evaporating into air, acting in two ways, and giving your skin doubled protection.

Since hydrated or moist skin reduces the appearances of skin wrinkles, it makes sense to say that hyaluronic acid is also useful in treating skin wrinkles. It also works well for people who battle dry skin because of its skin moisturizing properties.

Hyaluronic Acid for skin

Given all these facts, it is important to note that hyaluronic acid, aside from the natural aging process, can decrease or be negatively affected by other things as well. Tobacco smoking, exposure to pollution, and ultraviolet radiation from the sun all contribute to the damage to our hyaluronic acid. So it is vital to keep your habits healthy and avoid as much exposure as possible to pollution. For UV rays from the sun, sunblock can help, too.

2) Hyaluronic Acid Helps With Joint Pain

Aside from skin, hyaluronic acid can also be found in our joints, specifically in-between the spaces of your bones, as it keeps them well-lubricated to avoid dry friction against one another. Once the bones are less lubricated, it causes them to grind one another, which can be very painful on our part.

If you are suffering from osteoarthritis, a degenerative joint disease that is caused by the wear and tear on your joints as time goes by, hyaluronic acid can help you with that specific problem.

Hyaluronic Acid for back arthritis

3) Hyaluronic Acid Can Speed Up Healing

Do you know that hyaluronic acid, aside from keeping our skin moisturized, also plays a key role in healing wounds?

Since it naturally occurs and is present in our skin, hyaluronic acid can play a key role in healing our wounds. Specifically, its concentration increases if your skin is wounded and needed to be repaired. Hyaluronic acid will regulate the inflammation levels on your wound, and it will signal your body to build more blood vessels in the area to quickly cover up your wounds.

For the same mechanism, hyaluronic acid is useful when treating and dealing with gum diseases and helps in healing them after a major tooth surgery.

Hyaluronic Acid For Wounds

4) Hyaluronic Acid Can Help Relieve Dry Eyes And Eye Discomfort

Around 1 out of 7 older adults suffer from dry eye simply because their tear production reduced or their tears evaporate too quickly. Since hyaluronic acid is great at keeping water retention and moisture, it is no wonder that aside from skin, hyaluronic acid is also used to treat dry eye and other related eye discomforts.

Eye drops that contain around 0.2-0.4% of hyaluronic acid have been shown not only to reduce the dryness of one’s eye but even to improve eye health itself. In fact, even contact lenses are modified to contain a slow-release of hyaluronic acid so that your eyes get its moisturizing benefits and keep them from being dry,

Although hyaluronic acid is used to keep our eyes from being dry, there’s still more to know about the effects and benefits of hyaluronic acid to our eyes – and that can come with future research.

Hyaluronic Acid for eye discomfort

5) Hyaluronic Acid Can Help Preserve Bone Strength

Recent animal research has been done to investigate and test the effects and limits of hyaluronic acid supplements on animal bone health.

For two studies, it is shown that hyaluronic acid supplements can help in slowing down the rate of bone loss for rats with osteopenia.

For another study, it is shown that high doses of hyaluronic acid can increase the activity level of osteoblasts, cells that are responsible for building new bone tissue.

When it comes to humans, though, it is unclear how hyaluronic acid helps strengthen our bones. However, the results of animal research are promising for humans.

Best Hyaluronic Acid Supplements for bone health

How To Take Hyaluronic Acid

For supplements, hyaluronic acid supplements can be easily found in drugstores, health shops, and health food stores. You can also purchase hyaluronic acid online. Typically, you do not need a prescription to purchase hyaluronic acid supplements, but for some forms, such as injectable hyaluronic acid, you do. Most hyaluronic acid supplements are sold in tablets or capsules, though liquid formulations are available as well.

As for dosage, there is no universal standard so far. 200mg is often the recommended dosage, though some doctors advise a 1,000mg daily intake. But keep in mind that a higher dosage does not necessarily translate to more effectiveness.

Hyaluronic Acid Forms

Does Hyaluronic Acid Really Work?

Yes, assuming it is taken correctly and under proper circumstances, hyaluronic acid does work. After all, it is a natural moisturizer for your skin and lubricant for your bones and joints, so depending on your specific health ailments, it could help you considerably.

Is Hyaluronic Acid Right For You?

If you need to rejuvenate and moisturize your skin, or if you need any help in lubricating your bones and joints, hyaluronic can perfectly work for you.

Hyaluronic acid is safe for most people, assuming it is appropriately taken and under the right circumstances. As long as you take it in the proper dosage, you should be fine with it.

Best Hyaluronic Acid Supplements

Doctor’s Best Hyaluronic Acid with Chondroitin Sulfate ($28) – Doctor’s Best provides quality supplements at a low and affordable cost. The only warning that comes with this version of hyaluronic acid is that it is not a good option for those with acid reflux issues.

1MD MoveMD


One of our top picks for hyaluronic acid is 1MD MoveMD. 1MD is a well-known supplement company with a large and popular product line including choices such as 1MD Complete Probiotics Platinum, 1MD KrillMD, 1MD BalanceMD, and many more. 1MD MoveMD is their take on fast-acting joint pain relief. MoveMD includes powerful ingredients such as ApresFlex Boswellia Serrata for joint health and antioxidant Zanthin Natural Astaxanthin. Its benefits include reducing joint pain, increasing mobility and flexibility, and reducing oxidative damage.


Reserveage Collagen Booster with Hyaluronic Acid

Reserveage Collagen Booster with Hyaluronic Acid

Reservage pairs hyaluronic acid with collagen in order to provide an incredible supplement for your nail, hair, and joint health. This supplement is a bit pricier than the Doctor’s Best option, but the added collagen is certainly a benefit.


Vitauthority Multi Collagen Protein


Vitauthority Multi Collagen Protein is a powdered supplement that combines collagen and hyaloronic acid. This supplement includes 50 mg of Hyaluronic Acid and 7.8 g of a multi source collagen complex. The collagen within Vitauthority Multi Collagen Protein is sourced from four different food groups and includes hydrolyzed bovine collagen peptides, hydrolyzed fish collagen peptides, chicken bone broth collagen concentrate, and eggshell membrane collagen. It provides benefits such as smoothing wrinkles, strengthening tendons and joints, promoting hair and nail health, and reducing inflammation, among others.


Glucosamine Hyaluronic acid chondroitin MSM Supplement

Glucosamine Hyaluronic acid chondroitin MSM Supplement

This hyaluronic supplement is both vegan and vegetarian friendly. This option is one of the more affordable products on the market, but it is still great quality! The only downside with these capsules is that they need to be taken three times a day, whereas the other options are once a day.


Pure Hyaluronic Acid Serum from Cosmedica Skincare

Pure Hyaluronic Acid Serum from Cosmedica Skincare

This product is specifically for the anti-aging, anti-wrinkle benefits that come from hyaluronic supplements. This serum is both natural and organic, touting a variety of skincare benefits. This is a great option for a consumer who is strictly trying to improve the quality and moisture of their skin.


Can I Stack Hyaluronic Acid Supplements With Anything? 

Hyaluronic acid is a relatively mild supplement that can be taken with pretty much any other supplement. The only warning is for breastfeeding mothers to seek medical advice before getting a shot.

Hyaluronic Acid Alternatives

Many consumers use hyaluronic acid to target their skin and receive anti-aging benefits. There are a variety of serums that do similar things, but hyaluronic acid has been shown to have the most significant impact. There are also quite a few skin supplements on the market, such as Vitality Skin Envy, that can also serve as alternatives for skincare.

If you are thinking about adding a hyaluronic acid supplement into your diet, now is a great time to try it out. Hyaluronic acid is a relatively easy and safe supplement to test that carries a variety of benefits. If you start taking hyaluronic acid and experience any negative symptoms, contact a medical professional for help.

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Leslie Waterson

Leslie has been passionately involved in the health and fitness industries for over a decade. She is constantly reviewing the latest scientific research and studies in order to take a research-backed approach to lifestyle optimization. Her main areas of interest include nutrition and supplementation. Leslie shares her findings on Fitness Clone to help other health enthusiasts choose the products and routines that will help them achieve their goals.