NOVOS Core Review – Is It Right For You?

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By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

NOVOS Core Review

We all know that aging can’t be stopped completely. But what if it could be slowed down?

Well, that’s been the focus of many so-called longevity supplements lately, including one product called NOVOS Core.

In this article we’ll take a look at NOVOS Core to see if it really has any benefits for aging and longevity, and who might benefit from it.

Ready to learn more? Let’s dive into this NOVOS Core review!

Things to Consider

  • NOVOS Core contains 12 active ingredients to target root causes of aging
  • There is specific clinical research on NOVOS Core showing several benefits
  • The overall product quality is high and backed by researchers, doctors, and scientists. 
  • It’s rather pricey at $2.63 to $3.63 per serving, but the benefits may still be worth it for those who can afford it
  • Due to the many ingredients, it may be able to replace some of the supplements you currently take

About NOVOS Core

NOVOS Core is an anti-aging and longevity supplement created by NOVOS. It’s a pretty complex formula with 12 active ingredients, all of which were selected by a team of scientists and doctors to target various root causes of aging.


With ingredients like alpha-ketoglutarate, fisetin, and pterostilbene, NOVOS Core is essentially designed to target aging at the cellular level, aiming to reduce DNA damage and enhance overall health and wellness. 

In fact, they say that the NOVOS Core formula is so strong and diverse that it can replace the equivalent of 19 pills worth of active ingredients, making it a sort of “all-in-one” formula for your health and vitality.

NOVOS Core Benefits

NOVOS Core is advertised to target 12 hallmarks of aging. They say that the ingredients work better over time too, so you’ll get even greater benefits the longer you take it.

In general, here are the main benefits claimed by NOVOS Core:

  • Slow Aging
  • Increased Energy
  • Improved Skin Health
  • Mood Support
  • Enhanced Cognition
  • Reduced Inflammation
NOVOS Core Benefits

Slower Aging

The main overarching benefit claimed by NOVOS Care is slower aging. They claim that all of their ingredients are research-backed in some way(s) to improve longevity and slow down the aging process. 

In particular, ingredients such as pterostilbene and alpha-ketoglutarate are designed to decrease DNA damage and promote longevity and health from the cellular level. 

Increased Energy

NOVOS Core is claimed to increase energy levels. Ingredients such as malate are designed to increase cellular energy production. And there are other ingredients involved in energy metabolism such as magnesium and rhodiola which may help control stress and boost energy levels too.

Improved Skin Health

Another advertised benefit of NOVOS Core is improved skin health. First, this formula has specific ingredients such as hyaluronic acid which they say directly improves skin health and hydration.

And there are other ingredients like vitamin C which may offer antioxidant support for improved skin appearance and reduced skin damage.

Mood Support

There’s kind of a stereotype out there that older people are very cranky and irritable. Well, NOVOS Core is designed to offer mood support with ingredients such as lithium and magnesium, which may support healthy brain aging and neurotransmitter balance.

Enhanced Cognition

An additional brain benefit of NOVOS Core is enhanced cognition. They claim that a number of ingredients can reduce brain inflammation and support healthy brain aging. 

Plus, there are specific cognitive-enhancing compounds such as theanine and Rhodiola which they say offer further brain-boosting benefits.

Reduced Inflammation

NOVOS Core also is promoted to reduce inflammation and oxidative stress, which could have a carryover effect into many other benefits since inflammation is often a causative factor in health issues.

Pterostilbene, ginger, and alpha-ketoglutarate are just a few of the compounds that are advertised to decrease inflammation from the cellular level and control DNA damage, leading to a healthier internal state. 

Summary of Benefits

So, altogether, NOVOS Core certainly doesn’t hold back on the claimed benefits, making it seem like a frontrunner anti-aging supplement.

But how much of this is true? And is it really as good as advertised?

Read on to find out!

NOVOS Core Ingredients

There are 12 active ingredients in NOVOS Core, which are all designed to offer various anti-aging effects.

Below are all of the NOVOS Core ingredients:

  • Vitamin C
  • Magnesium Malate
  • Glycine
  • Calcium Alpha-Ketoglutarate
  • GreenGrown Glucosamine Sulfate
  • Rhodiola 
  • Theanine
  • Hyaluronic Acid
  • Fisetin
  • Ginger
  • Pterostilbene
  • Lithium
NOVOS Core Supplement Facts

Vitamin C (100mg)

Vitamin C is an essential vitamin most known for its antioxidant effects. The strong antioxidant and anti-inflammatory effects may protect against cellular damage and as a result, contribute to healthy aging. 

Magnesium (304mg)

Magnesium is an essential mineral with hundreds of roles in the body. It can help control inflammation, support metabolism, reduce stress, and maintain a healthy brain and heart. 

Getting enough magnesium seems very important to help ward off age-related issues such as poor sleep, muscle pain, hypertension, and general inflammation. 

Malate (1,700mg)

Malate is a natural compound with pivotal roles in energy metabolism. Basically, it helps the cells to produce energy which can lead to lower fatigue and maybe even better exercise capacity.

It’s often combined with citrulline to form citrulline malate, which is a pre-workout ingredient. 

Glycine (2,000mg)

Glycine is an amino acid that may have a number of benefits for aging. For example, glycine may increase cellular maintenance and repair, while also controlling inflammation.

In general, glycine is thought to have solid longevity potential

Calcium Alpha-Ketoglutarate (1,110mg)

Calcium alpha-ketoglutarate is a form of alpha-ketoglutarate (AKG), which is a metabolite with many potential roles for longevity.

It increases energy production, helps to control cellular stress and inflammation, and may even interact with various genes that turn “off” or “on” different aging pathways. 

GreenGrown Glucosamine Sulfate (1,000mg)

GreenGrown is a vegan, trademarked form of glucosamine sulfate. You may have heard of glucosamine due to its roles in joint health and joint protection. In fact, many joint supplements like Performance Lab Flex use it.

This generally seems to be backed up since glucosamine can reduce collagen degradation and reduce joint pain. There’s also some evidence that it can improve metabolism too. 

As for other potential anti-aging effects, there’s not as much research. 

Rhodiola (300mg)

Rhodiola is an herb with a long history of use to control stress-related problems. Basically, Rhodiola helps the body stay in balance even when faced with chronic stress. It is often used to lower anxiety and depression, improve mood, boost endurance, and enhance cognition. 

Rhodiola also seems to protect the brain, heart, and other body systems from inflammation and oxidative stress, which makes it possibly useful as an all-around anti-aging product. 

L-Theanine (150mg)

L-theanine is an amino acid most known for its anti-anxiety and anti-stress properties due to its effect on alpha brain waves and certain brain chemicals.

Theanine may also boost cognitive function and could help protect against age-related cognitive decline. So, it’s overall a good ingredient for the brain in particular.

Hyaluronic Acid (100mg)

Hyaluronic acid is a compound mainly used for skin health. It can increase collagen synthesis, reduce skin damage, and help to regenerate the skin. 

So, overall there is evidence that hyaluronic acid is effective for maintaining healthy skin as you age. This includes reduced wrinkles, greater hydration, and improved elasticity.

Many beauty supplements like HyaCera also use hyaluronic acid to achieve a younger, healthier look. 

Fisetin (100mg)

Fisetin is a type of polyphenol that may control aging at the cellular level. There is evidence that fisetin can help to ensure normal and healthy cellular function while limiting cell damage. 

Ginger Root (100mg)

We often think of ginger as just a spice. But there are health benefits too, such as for digestion and gut health.

On top of that, ginger also has antioxidant, anti-inflammatory, immune-regulating, and metabolism-enhancing activities that could make it a good compound for longevity and anti-aging.

Pterostilbene (50mg)

Pterostilbene is a derivative of resveratrol, which is a compound you may have heard of due to its effects on anti-aging too (not to mention its existence in grapes, red wine, and other foods).

Well, pterostilbene actually seems to be more effective than resveratrol for some benefits. Specifically, pterostilbene may be a strong anti-inflammatory compound, and it can control DNA damage and overall cellular health. Plus, it’s better absorbed than resveratrol.

Several other anti-aging products use pterostilbene, including Invity Ultimate NMN 12000.

Lithium Aspartate (20mg)

Lithium aspartate at 20mg provides 1mg of lithium, which is a compound often used as a mood stabilizer.

The main benefit of lithium seems to be for brain health. Specifically, lithium can ultimately improve mood, which in turn, might decrease the negative effects that depression and poor mood would otherwise have on aging. 

Does NOVOS Core Work?

Overall, it is very likely that NOVOS Core will work to aid in healthy aging. Of course, we can never say that a product is guaranteed to extend your lifespan or decrease aging, as there are way too many factors.

But when looking at NOVOS Core, it’s clear that the makers took the time to put in well-researched ingredients that have evidence behind them for anti-aging and longevity.

In fact, NOVOS Core has been subject to multiple research studies. And there is evidence on this specific formulation that it can reduce DNA damage, improve skin health, and ultimately slow down certain biological markers of aging.

NOVOS Core Powder

How Does NOVOS Core Compare?

NOVOS Core is one of the best longevity formulas on the market due to the ingredient quality, dosages, and diverse mechanisms and benefits that are potentially offered. Rather than including just one or a couple of ingredients, NOVOS Core has several top-notch anti-aging ingredients to possibly target different root causes of aging, which makes it a diverse formula.

For example, even when we look at one of the top anti-aging supplements in Invity Ultimate NMN 12000, NOVOS Core still seems to provide a more well-rounded approach. With that said, Invity NMN 12000 still is a great choice since it has NMN, pterostilbene, alpha-lipoic acid, and other compounds that may support healthy aging, reduce inflammation, and boost antioxidant effects.

Now, another thing about NOVOS Core that’s beneficial is the clinical research behind it, whereas most products typically do not. And based on what we’ve seen, there are potential benefits for brain function, mood, energy, heart support, metabolism, and several other areas, so it really is a comprehensive anti-aging formula.

Who is NOVOS Core Best For?

NOVOS Core is best for individuals who are looking to target various root causes of aging and want to boost overall health from the cellular level.

It can be used by young adults, middle-aged individuals, and older adults alike. 


  • Research-backed ingredients
  • Good dosages for the most part
  • The product itself is clinically studied with good results
  • Third-party tested
  • Vegan and all-natural


  • High-priced (some may not be able to afford it)
  • Need to purchase a year-long subscription to save the most money

How to Take NOVOS Core

NOVOS Core comes in sachets. Add one sachet of powder to water, juice, smoothie, yogurt, tea, or drink of choice.

It’s best when taken with or after a meal. And you can take up to two sachets per day.

NOVOS Core Drink

Is NOVOS Core Safe?

NOVOS Core should generally be safe to take. Some people may experience side effects such as:

  • Upset stomach
  • Nausea
  • Allergic reactions
  • Headache

NOVOS Core is made in a cGMP, FDA-registered facility and is third-party lab tested for purity and potency.

This supplement is free from major allergens and is vegan, sugar-free, non-GMO, and all-natural.

Where to Buy NOVOS Core

You can buy NOVOS Core on the NOVOS website.

NOVOS Core Website

Each box comes with a one-month supply (30 sachets). The regular price is $109, although you can save money with a monthly, semi-annual, or annual subscription.

The NOVOS Core prices are:

  • Monthly – $98
  • Semi-Annual – $558
  • Annual – $950

So, depending on what you choose, NOVOS Core costs anywhere from $2.63 to $3.63 per serving, so it’s definitely not a low-priced supplement. 

Anti-aging supplements typically are higher-priced though, although NOVOS Core still is a bit high even with that considered. Then again, it also contains more ingredients and more possible benefits than most longevity supplements, so it seems pretty fair-priced altogether.

Verdict: NOVOS Core Review

Ultimately, NOVOS Core is one of the best anti-aging supplements out there and seems worthwhile, as long as you can afford it.

Their formula certainly isn’t lacking in research-backed ingredients. In fact, there are many possible ways NOVOS Core could help with aging, ranging from improved cellular health, to decreased inflammation, to better energy production, and much more. 

And it’s also one of the few supplements that’s actually been subject to clinical research, with positive and intriguing results at that. 

Yet, it’s definitely not cheap, with the lowest price at just under $3 bucks per serving. But given the potential benefits, we’d say it’s worth trying out if you can afford it and are someone who really wants to try and boost cellular health.

Overall Rating:
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Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.