Best Garlic Supplements – Is It All In The Allicin?

People worldwide have believed in the almost mystical powers of the vegetable, garlic, for eons. (And, yes, garlic is considered a vegetable rather than an herb botanically). Bram Stoker added to the allure of garlic when he introduced it in his 1897 novel, Count Dracula.  In the book, Van Helsing uses garlic to ward off the vampire, Dracula. In folklore, garlic was used as a protective agent against vampires, evil spirits, disease, and mosquitos, another bloodsucker.

Today we aren’t quite as concerned with garlic’s ability to repel evil spirits or vampires, and yes, some people still use it repel mosquitos. However, modern science is very much aware of the other health benefits of garlic, and by extension, garlic supplements. Natural garlic and garlic supplements have been the subject of numerous clinical trials, with somewhat conflicting results.

At the heart of the debate is a compound known as allicin. In this “Best of” article, we will detail the science behind allicin, garlic, and garlic supplements. We’ll provide a topline review of several clinical trials testing the importance of allicin in delivering garlic’s health benefits. We will detail the benefits of garlic supplementation, dispel a few myths along the way, and finally, we will provide our choices for the best garlic supplements on the market today. As always, our selections are unbiased as we have no interest or affiliation with any of the products or brands selected.

Garlic supplements

The Science Behind Allicin – For Combating heart Disease

Whole garlic contains the amino acid alliin. When chewed or crushed, alliin combines with alliinase the enzyme that catalyzes the conversion of alliin to make allicin. Allicin is the main active ingredient in garlic, which produces a series of other sulfur-containing compounds such as diallyl disulfide.

Quoting the NCBI (National Center for Biotechnology Information) …  Studies show that garlic and its bioactive constituents exhibit antioxidant, anti-inflammatory, antibacterial, antifungal, immunomodulatory, cardiovascular protective, anticancer, hepatoprotective, digestive system protective, anti-diabetic, anti-obesity, neuroprotective, and renal protective properties.

Those are significant health benefits from this one ingredient/supplement and explain the multitude of clinical trials. One prominent manufacturer in the garlic space, the Wakanuga of America Company, makers of the Kyolic brand, has conducted over 750 clinical trials.

NCBI listed cardiovascular protection as a benefit, and much of this article will focus on these heart health and blood pressure claims. It is believed that allicin also aids in the release of nitric oxide in your blood vessels, relaxing them, and lowering your blood pressure. Lower blood pressure is beneficial for your heart and the entire vascular system.

We’ll revisit allicin and its role in cardiovascular health later in this review and present a dissenting viewpoint.

garlic supplement gel

Check Out Our 9 Top Rated Supplements
Our team has reviewed hundreds of popular supplements - these are our 9 favorites.
Click Here to check out the list.


Let us get back to our vegetable, garlic, a species in the onion genus, Allium. Relatives in the Allium family include the white onion, the red onion, yellow onions, shallots, leeks, and chives. Garlic is native to Central Asia and northeastern Iran but has long been a popular seasoning worldwide. In the U.S., Gilroy, CA, is our nation’s “garlic capital.”

Garlic is incredibly nutrient-dense. It is a rich source of Vitamin B6 and contains, B2, B3, folate, Vitamin C, calcium, iron, magnesium, manganese, phosphorous, potassium, sodium, and zinc. There are 600 varieties of garlic in the world, with the two main subspecies being hardnecks and softnecks.

Many people still believe the medicinal value and health benefits of garlic are best unlocked when consumed raw.

Allicin in garlic

Garlic Supplements – Explained

Garlic supplements available on the market today typically fall into one of four categories:

  1. Garlic oils – Garlic essential oil and vegetable oil base.
  2. Garlic powders – A form of dehydrated and pulverized garlic. Powders are usually delivered in a tablet or capsule form with parsley, mint, or citrus to decrease odor.
  3. Garlic oil macerates – Garlic cloves, or garlic powder mixed into vegetable oil and then encapsulated.
  4. Aged garlic extract – Made from organically grown garlic, which is crushed and then naturally cold-aged for up to 20 months, removing the odor in the process.

In our opinion, the best garlic supplements feature certified organic, Non-GMO, and odorless garlic.

Important Note: allicin is not present in many of the top garlic products due to its instability and reactivity. Brands often express their “potencies” in theoretical amounts of the raw garlic used to distill its product. Other brands may use a powder that contains alliin and alliinase. You will remember that alliinase is the enzyme that converts alliin to allicin. This combination, when added to water, converts to allicin in a test tube. However, a test tube is a very different environment from our digestive tract.

Science has, for years, deemed allicin as the compound responsible for garlic’s health benefits. Once again, in test tubes, allicin has shown an ability to kill bacteria and fungus. However, research also indicates that the garlic supplements used to demonstrate its health benefits contain insignificant amounts of allicin, if any. The benefits of garlic are most likely the result of a synergy of the various compounds absorbed by the body.

Clinical Trials Of Garlic Supplements

We return to the NCBI (National Center for Biotechnology Information) to provide an overview of garlic clinical trials and the role of allicin. Most clinical trials since the 1980s have used garlic powder products, from dehydrated and pulverized whole clove supplements, to study the effects on cholesterol and blood pressure. To be fair, results are mixed, there appears to be a benefit on blood pressure levels for hypertensive subjects, although cholesterol reaction found little to no effect. Due to inconsistencies in the studies, such as variance in dose, product types, and very importantly, the identification of active compounds and bioavailability, results are inconclusive.

The studies confirm the efficacy of allicin in vitro; however, question the allicin bioavailability from the various supplements. Stated differently, allicin is not present in many of the top garlic products due to its instability and reactivity.

best garlic supplements

Garlic Supplement Benefits

Speaking of benefits … a product which is antioxidant, anti-inflammatory, antibacterial, and antifungal, and provides cardiovascular protection, is anticancer, protects the digestive system, is anti-diabetic, anti-obesity, and neuroprotective has awesome potential.

As noted, recent findings indicate garlic has a beneficial effect on high blood pressure. Eleven new studies of garlic supplements and blood pressure showed garlic reduced systolic blood pressure by an average of 4.6 mmHg.

Additional potential benefits of garlic supplementation:

  • Reduced Chance of Cold and Flu – and shorter duration
  • Prevention of Heart Disease
  • Anti-Aging – Allium vegetables are a good source of antioxidants and contain compounds that may have an anti-aging effect by counteracting the glycation process.
  • Anti-bacterial and Anti-parasitic – Garlic has antibiotic properties and is considered one of our best natural options because its chemicals have antibacterial, antiviral, and antiparasitic properties.
  • Cancer Prevention – several studies have indicated an association between daily consumption of garlic and prevention of stomach and colorectal cancers.

In alternative medicine, garlic/allicin is said to protect against the following health problems:

  • Atherosclerosis
  • Diabetes
  • High Blood Pressure
  • High Cholesterol

Author Dan Buettner has published the most thorough investigation of centenarians in his bestseller, Blue Zones. It is an intriguing read and offers fascinating insights as to how and why certain peoples around the world, those living in what he refers to as Blue Zones, enjoy such long lives. One of the factors possibly influencing their health, vitality, and longevity, is their diet, emphasizing vegetables such as beans and garlic and onions in the Allium family.

garlic supplement for overall health

Dispelling The Garlic Myths

Garlic Does Not Detoxify Your Blood

Unfortunately, most products, including garlic, that claim to detoxify your body are not true. These claims are not backed by scientific evidence.

Garlic Does Not Combat Acne

Although those suffering from acne will try almost anything to clear their skin, garlic is not the solution. We couldn’t find any medical research to support anti-acne claims.

How Much Garlic Do You Need

World Health Organization recommendations:

  • 2 grams to 5 grams of fresh garlic
  • .4 gram to 1.2 grams of dried garlic powder
  • 2 milligrams to 5 milligrams of garlic oil
  • 300 milligrams to 1,000 milligrams of garlic extract

As an example, our top recommendation, Kyolic Aged Garlic Extract’s recommended serving is two capsules, 600 mg, twice per day, or 1,200mg.

garlic cloves

What Forms Of Garlic Supplements Are Available?

As previously stated, there are four primary types of garlic supplements available today: garlic oils, garlic powders, garlic oil macerates, and aged garlic extract.

Is Garlic Supplementation Safe?

With our endorsement, we also must note that garlic supplementation can have side effects, such as diarrhea, heartburn, gas, and nausea. And, for people in certain situations, garlic can have dangerous side effects.

For Those Preparing For Surgery

Garlic can disrupt anti-coagulants, so before any surgery, discuss your garlic supplement with your physician in case you need to stop taking them. Also, garlic supplements may not be advisable for those taking blood-thinning medication.

Garlic Allergies

Some people suffer an allergic reaction after consuming garlic. The most common symptoms include rash, headache, and high temperature. Although rare, garlic has caused anaphylaxis, a potentially fatal allergic reaction.

Topical Application – Again Garlic Is Not For Treating Acne

Garlic contains a potent chemical compound, diallyl disulfide. This compound can irritate the skin and even cause a burn that may take months to fade.


Being a part of the onion family, garlic is poisonous to pets. Never feed onion related foods, either raw or cooked, to pets.

As we always recommend, consult with your medical professional before adding a garlic supplement to your regimen. Even though it’s a natural product, garlic may still interact with other medications.

Will Garlic Supplements Benefit Me?

Seldom are we as definitive in endorsing a product as we are with garlic. Whether you achieve your daily recommended dosage via whole food, garlic powder supplement, garlic oil, or aged garlic extract, we’re confident you will receive many of the promised health benefits. If you have concerns regarding heart health and blood pressure, we think this is a no-brainer to add to your regimen.

Best Garlic Supplements

When selecting the best garlic supplements, we scoured the market for brands that adhere to the following:

  • Product attributes; odorless, Organic Certified, Non-GMO
  • We ensured the products are manufactured in a certified cGMP facility (Good Manufacturing Practices)
  • We looked for companies and brands that have independent third-party testing and money-back guarantees

Kyolic Aged Garlic Extract – Cardiovascular, from Wakanuga of America Company

Kyolic Aged Garlic Extract - Cardiovascular, from Wakanuga of America Company

Wakanuga offers the most extensive line of garlic supplements on the market today under the Kyolic brand name. They dominate the market in the natural products space, particularly in brick and mortar retailers. Kyolic has sixteen sku’s featuring aged garlic extract as a primary ingredient in liquid, capsules, vegetarian capsules, tablets, and soft gels. They meet or exceed all our criteria in terms of manufacturing and third-party testing. With over 750 scientific studies and counting, Kyolic Aged Garlic Extract is the number one choice of consumers looking to promote heart health and address blood pressure and circulation.

Kyolic Cardiovascular contains 600 mg of odorless, aged garlic extract in two capsules or tablets (per serving). They are designed to support and strengthen your cardiovascular system by maintaining circulatory function and promoting overall heart health.

Three-hundred capsules retail for $12.99 online at, or $11.84 at

Odorless Garlic, 1500 mg, from NaturaLife Labs

Odorless Garlic, 1500 mg, from NaturaLife Labs

Each NaturaLife soft gel capsule delivers a full 1,500 mg of garlic per serving, earning it the Maximum Strength label. The product is made with fresh California grown, organic garlic, free of chemical processing, and contains no fillers, magnesium stearate, dioxides, preservatives, gluten, sugar, yeast, or starch.

Manufactured in an FDA registered facility in accordance with Good Manufacturing Practices and third party tested. Supported by a 100% Money-Back Guarantee.

One-hundred and fifty soft gels sell for $11.99 on

Odorless Garlic Extract, from Sundown

Odorless Garlic Extract, from Sundown

Sundown is a brand in the Nature’s Bounty Company portfolio.  Other trusted Nature’s Bounty brands in the natural product’s space include Met-RX, Pure Protein, Body Fortress, Solgar, and, of course, Nature’s Bounty. The company manufactures and markets more than 16,000 nutritional supplement items.

All Nature’s Bounty products and ingredients are manufactured in cGMP facilities and subjected to independent third-party testing by United States Pharmacopeia and STR (Specialized Technology Resources).

Made with odorless garlic extract and free of artificial colors, flavors, and sweeteners. All Sundown products are Non-GMO certified.

At 250 soft gels for $8.30, this is one of the best values in the category.

Garlic Force, by New Chapter

Garlic Force, by New Chapter

In a unique approach, New Chapter manufactures Garlic Force with dual extracts of garlic plus complementary herbs like ginger and organic oregano to add the whole-food benefits of garlic. The product is Non-GMO Project Verified, 100% vegetarian, gluten, dairy, and soy-free, with no synthetic fillers, and no artificial flavors or colors.

This more premium formulation comes at a cost, 30 vegetarian capsules retail for $23.97.

Garlic Supplement Alternatives

For those seeking the heart health benefits of garlic, there are two popular supplement options, CoQ10 and Omega 3. Consuming more garlic in your diet is another option. In fact, using garlic instead of salt to flavor food is also an excellent way for people to manage their high blood pressure.

To Summarize: Garlic Supplements And Your Health

Regardless of who is more accurate in the “allicin versus the synergy of garlic compounds debate,” we are confident a garlic supplement can be beneficial. We’ve discussed garlic supplements, its benefits, and the best garlic supplements. Most garlic supplements are relatively inexpensive, so the cost of adding them to your regimen is minimal.

You May Also Like
How To Cleanse Your Gut – 9 Natural Ways To Detox

How To Cleanse Your Gut – 9 Natural Ways To Detox

The word 'detox' often generates skepticism, particularly among those who have yet to try one. Detox, as a word, tends to get thrown around a lot without much explanation. Understandably so, given the controversy that surrounds it.  There are many detox regimens...

How To Speed Up Digestion – 5 Proven Tips And Tricks

How To Speed Up Digestion – 5 Proven Tips And Tricks

Our digestive system is composed of the liver, gastrointestinal tract, gallbladder, and pancreas. Its responsibility is to break down foods and liquids so they can become basic chemical components like carbohydrates, proteins, and fats. Used as energy for cell...

Pros And Cons Of Intermittent Fasting – The Ultimate Guide

Pros And Cons Of Intermittent Fasting – The Ultimate Guide

Intermittent Fasting (IF) involves cycling set periods of abstaining from food, followed by a feeding window. It's become a popular diet option and promises a wide range of health benefits, including weight loss. But, are there downsides to this eating pattern as...

Best Elderberry Supplements – Our Top 5 Choices

Best Elderberry Supplements – Our Top 5 Choices

If you have not heard of elderberries yet, they are one of the most popular and commonly used plants for medicinal purposes around the world. This berry, just like other medicinal herbs and plants, was discovered hundreds of years ago and has been used since ancient...

What Can You Drink While Fasting – The Picks That Help Your Diet

What Can You Drink While Fasting – The Picks That Help Your Diet

Timothy Ferris of the 4-Hour Workweek and 4-Hour Body fame is also a favorite author. In one of his latest works, Tools of Titans, he interviews billionaires, icons, and world-class performers, such as Arnold, Kevin Costner, Jamie Foxx, Jack Dorsey, Laird Hamilton,...

Disclosure: Some of the links in our articles are from our advertisers. Learn more about how we make money.



Latest Fitness Profiles

Steve Howey

facebooktwitteryoutubeinstagramSteve HoweyActorBorn: 1977Born in Texas, Steve Howey moved to Colorado in high school, and then attended Northeaster Junior College for 2 years on a basketball scholarship. He guest starred on several TV shows in the 90s icluding ER and...

Justin Bieber

facebooktwitteryoutubeinstagramJustin BieberMusicianBorn: 1994Canadian-born Justin Bieber was raised by his grandparents. He learned to play the piano, drums, guitar, and trumpet when he was growing up. After Bieber won a local signing competition at age 12, his...

Anna Kaiser

facebooktwitteryoutubeinstagramAnna KaiserFitness ProfessionalBorn: 1980Canadian-born Anna Kaiser attended UC Irvine and had the intention of pursuing a career in dance. She appeared in Carnegie Hall in 2007 and as a lead dancer in the 2007 Disney film Enchanted. In...

Sterling K Brown

facebooktwitteryoutubeinstagramSterling K BrownActorBorn: 1976Sterling Kelby Brown was born in St. Louis, Missouri and is 1 of 5 children. His father died when he was 10. Brown graduated from Stanford University in 1998 with a degree in acting, then earned a Master of...

Jean-Claude Van Damme

facebooktwitteryoutubeinstagramJean-Claude Van DammeActorBorn: 1960Jean-Claude Van Damme is the stage name of Belgian actor Jean Claude Van Varenberg. He began practicing martial arts at age 10, started competing at 15, and earned a black belt in karate when he was...

Latest Reviews

Adrenal-T Review – Is This Life Seasons Supplement Legit?

Life Seasons’ philosophy is one that values life, and they have a desire to help protect, sustain, and see yours flourish. They also believe in your body’s own innate healing forces and their own ability to make life-giving health choices—something which drives them...

Anser Vitamins Review – A Look At Their Women’s Multivitamin

Vitamins are an important and essential part of maintaining health and general well-being. But sometimes, it is simply not possible to get in enough vitamins. Whether you are too busy to eat nutritious meals all day long or you simply can’t get in the suggested amount...

Kori Krill Oil Review – Is This The Right Supplement For You?

Have you ever heard of fish oil? It’s one of the most popular supplements in the entire world and comes with an insane amount of benefits to the human body. Of course, not everyone is a fan of fish oil, and not everyone’s body effectively absorbs it. That’s why so...

4D Premium Review – Will This Supplement Up Your Energy Levels?

If you’re looking to increase your day-to-day energy, then trying out a supplement designed specifically to provide you with the energy you're craving might be a good idea. The issue? There are many different energy supplements on the market, and it can be...

Related Articles

Best Supplements To Take While Fasting

Speak to anyone in the gym today about diet, and we guarantee you will hear about the Keto, Paleo, and of course, intermittent fasting. For all its current popularity, fasting is far from new. It’s been practiced in various forms, total abstinence, severe calorie...

Best Supplements For Men

The best supplements for men is an ambitious topic. There is no one best supplement or stack of supplements that can address every mans’ specific needs or aspirations. Sure, there is a Car of the Year, but there is also a Sports Car of the Year, Truck of the Year, and...

Best Casein Protein Powder – Top 8 Choices For Your Health

How important is protein? You can live your entire adult life without carbohydrates, up to six months without dietary fat, but only about seventy days without protein. Protein, one of the three main macronutrients in food, has amino acids, carbon, hydrogen, oxygen,...

How Do Keto Pills Work? – The Answers You’re Looking For

If you are following the ketogenic or keto diet (or you’re about to follow it), you may have heard about keto pills. Ketogenic pills are supplements that add ketones to your body to better supplement your body’s ketosis. The ketones added to your body are called...

Best Personalized Vitamins

Best Personalized VitaminsAdvertising DisclosurePersonalized vitamins are the new way to meet your nutrient and vitamin requirements each day. There are quite a few companies now that offer subscriptions for individualized and unique everyday vitamin packs. This...

Top Rated Supplements
Best Supplements

Our team has reviewed hundreds of popular supplements - these are our 9 favorites.

Check Out the List

Pin It on Pinterest

Share This