Best CoQ10 Supplements

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By Leslie Waterson

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

best coq10 supplements

CoQ10 supplements have become increasingly popular as people have discovered their energy-boosting properties as well as their ability to fight off chronic diseases. You can find a variety of these supplements in your local grocery store, online, and even at places like Target. 


These supplements are not only great to help fight against chronic diseases, but they have been shown to have anti-aging properties, as well as aid in mitochondrial diseases. There are a variety of benefits that come potentially come with taking CoQ10, which we will dive into. We’ll also provide you with our list of the very best CoQ10 supplements that are worth using.

Let’s start by looking at our top-rated supplements before diving into some details on how CoQ10 works and how it may benefit you.

Best CoQ10 Supplements

Our team has reviewed over 1,000 health supplements. Here are our top-rated CoQ10 supplements.

LiveWell CoQWELL

Best CoQ10 Pills

LiveWell CoQWELL is a gluten-free, dairy-free, and preservative-free CoQ10 supplement.

CoQWELL includes a highly bioavailable CoQ10. The product uses a patented, oil-based formulation for its CoQ10 that is designed to promote greater absorption rates than other similar supplements.

It also contains rice bran oil and pro-vitamin A and provides benefits, including supporting healthy heart function, maintaining energy levels, and benefiting immune function.

CoQWELL is also reasonably priced and backed by a money-back guarantee.

LiveWell CoQWell

Manna Liposomal CoQ10

Best Liquid CoQ10

Manna Liposomal CoQ10 is a liquid CoQ10 supplement for people who prefer not to take pills.

This product uses a liposomal delivery method that helps your body absorb the CoQ10 10x better than competing supplements.

Manna Liposomal CoQ10 support sustained energy, immune support, heart health, and brain function.

The product is made in the USA and backed by a 90-day money-back guarantee.

manna liposomal coq10

What Is CoQ10?

Coenzyme Q10 (or simply CoQ10) is a compound that can be naturally found in your body. Coenzyme Q10 is said to have antioxidant effects, which is very essential in properly functioning cells. One of the main roles of CoQ10 is to help produce energy, making it an essential compound.

According to research, Coenzyme Q10 can be helpful in preventing some major and common diseases such as migraines, diabetes, and Alzheimer’s disease. Coenzyme Q10 is also shown to reverse signs of aging.

The levels of CoQ10 inside our body decrease over time, so it’s important to take it as you age.

CoQ10 Supplement Benefits

Coenzyme Q10 can help us in a variety of different areas of our health. Here are some of the science-backed benefits of supplementing with CoQ10.

CoQ10 tablets

1) CoQ10 Can Help With Diabetes

If you have diabetes, pre-diabetes, or are prone to diabetes, CoQ10 can help you prevent or deal with it. CoQ10 may help improve diabetic neuropathy and insulin sensitivity in people who have diabetes. 

For instance, according to a study conducted in 2018, fifty patients who have diabetic neuropathy were given either a placebo or 100mg of CoQ10 a day in a span of twelve weeks. Patients who took a regular dose of 100mg CoQ10 were shown to have a significant reduction in blood sugar and insulin resistance compared to the other group.

2) CoQ10 Can Help Manage Migraines

Migraines are a very painful and extreme form of headache. If you are struggling with a migraine, CoQ10 can help you deal with it.

Coenzyme Q10 is shown to help people suffering from migraines. For instance, according to one study published in Neurology, forty-two patients who suffered from migraines (without aura) received either a 100mg of CoQ10 or a placebo pill to be taken daily for three months.

The results? A little under half that took the 100mg of CoQ10 reported a decrease in migraine attacks of around 50% or even more. This is compared to those with placebo,  who only had a drop of around 14.4%

The American Headache Society and the American Academy of Neurology stated that Coenzyme Q10 can possibly be effective in preventing migraines and migraine attacks, but so far, this conclusion is only based on small and limited evidence.

Nevertheless, CoQ10 can be helpful if you are struggling with migraines.

3) CoQ10 Can Help Neurodegenerative Diseases Such As Alzheimer’s And Parkinson’s Disease

Some neurodegenerative diseases, such as Alzheimer’s, do not have an actual treatment yet, so, the best thing we can do is try to prevent it.

Only a few trials of CoQ10 have been done on people when it comes to Alzheimer’s and Parkinson’s. However, in an animal-based study, CoQ10 is shown to prevent the overproduction of beta-amyloid, a protein fragment that helps in forming brain plaques related to Alzheimer’s disease.

In a separate review published to the Neuropsychiatric Disease and Treatment, it demonstrated that CoQ10 can be used in treating neurodegenerative diseases such as Alzheimer’s and Parkinson’s, although more is yet to be known about this subject matter.

Although there is little concrete knowledge of how CoQ10 can help us against neurodegenerative diseases, it does show some promising signs.

4) CoQ10 Is Great For Heart Health

Coenzyme Q10 can be beneficial if you are having problems with your heart health such as heart failure, heart attacks, coronary artery disease, and atherosclerosis, according to one report in Pharmacology & Therapeutics.

In one study, coenzyme Q10 was shown to reduce oxidative stress, which is one factor that worsens some heart problems, as well as helps in widening our blood vessels – an essential factor when controlling blood pressure.

CoQ10 is also shown to be beneficial to cardiac cells, which in themselves are sensitive when we are CoQ10 deficient. So, if you need extra care for your heart health, CoQ10 can help you have and keep a healthy heart.

5) CoQ10 Can Lower And Regulate Blood Pressure

Whether or not CoQ10 can help regulate your blood pressure is a widely debated topic. Some research demonstrates that it can help lower your blood pressure, while other research shows it has little impact. 

According to a review published in the Cochrane Database of Systematic Reviews last 2016, scientists and experts gathered data from preceded published clinical trials to examine CoQ10 and blood pressure. The experts compared the effects of two groups – one that took CoQ10 and one that took a placebo when it comes to treating high blood pressure.

The analysis of the experts and scientists show that coenzyme Q10 may not help in lowering our blood pressure; this is contrary to the findings and conclusions of previous studies and reports. However, the reviewed studies were too small to be used to make such a big conclusion.

One thing is clear, however: that CoQ10 is good for the overall heart health (as mentioned above) and, in one way or another, it positively affects blood pressure as well.

6) CoQ10 Can Benefit Your Skin

Your skin is the largest organ in your body, and since it is exposed in the outside world, it often receives regular damages which we normally don’t even consider. Taking or applying CoQ10 directly to your skin can help in reducing the damage by increasing the energy production of your skin cells.

Also, those with low levels of CoQ10 are more prone to developing skin cancer, so it makes sense to keep your CoQ10 levels in check.

Forms Of CoQ10

As with many vitamins, minerals, and compounds, there are two ways to take CoQ10: either through supplements or by adding it to your diet. Keep in mind that, in some cases, trying to absorb a vitamin or compound (in this case, CoQ10) by adding it to your diet can be hard for your body. This is especially true if you have a track history of bad digestive health.

So, if you are going for the supplement route, here’s what you need to know:

When it comes to dosage, the recommended dosage of coenzyme Q10 will vary from person to person. It will depend on the following factors:

·  Your health status

·  Your age

·  Your current condition

The standard daily dosage of coenzyme CoQ10 will range from 60mg to up to 500mg. So far, the highest recommended dosage is 1,200mg. However, some clinical trials even used a whopping dosage of 3,000mg per day.

It is important to note that the recommended dosage of CoQ10 may vary depending on the supplement type you are using. For instance, ubiquinone, the inactive form of CoQ10 and also the one used by most supplements, is harder to absorb than ubiquinol.

If you want to incorporate coenzyme Q10 on your diet, you can get it on the following food sources:

  • Eggs
  • Organ meats
  • Nuts
  • Whole grains
  • Oily fish (such as salmon, mackerel, tuna, and sardines)

Does CoQ10 Really Work?

CoQ10 does work, although some benefits have to be further studied because they have not tested the full extent and limits of coenzyme Q10. For instance, the extent of CoQ10’s benefit in fighting off neurodegenerative diseases like Alzheimer’s, but for other factors, such as heart health and migraines, CoQ10 is proven to be beneficial.

Keep in mind that coenzyme Q10 naturally exists in our body. The amount just happens to decline in number as we age, which is why we need outside sustenance of CoQ10 through supplementation and specific foods in our diet to keep the numbers intact.

Who Should Take CoQ10 Supplements?

Under the right health circumstances or conditions, CoQ10 should be perfectly fine for you. In fact, as mentioned earlier, CoQ10 naturally exists in our body, so taking it either through supplementation or diet should not hurt.

Just be sure to be mindful of your dosage (as briefly explained above) if you decide to take CoQ10. If you are having problems with your heart, experiencing migraines, have diabetes, or experience other health problems, CoQ10 will definitely be beneficial for you.

CoQ10 Alternatives

There are a variety of similar supplements to CoQ10 but if you are looking for any of the six benefits mentioned above, give it a try first! 

If you are looking for supplements to aid in Alzheimer’s disease, try out Vitamin A, Vitamin B1, Vitamin B12, Vitamin B9, or Vitamin C. If you are looking for an increase in athletic performance you can try out Carnitine, Glutamine, Iron, Tyrosine, or a pre workout. If you are looking to decrease your chances of congestive heart failure, try Alpha-Lipoic Acid, Creatine, or Vitamin B1. 

Can I Stack CoQ10 With Anything? 

Like many supplements on the market, you can take CoQ10 with pretty much every vitamin or herbal remedy out there. Where you need to be careful is in taking it with specific types of medicine, blood thinners in particular. According to the Indian Heart Journal, CoQ10 has an excellent safety profile, making it a great supplement to test out.

If you are experiencing any health problems that might benefit from taking CoQ10, it might be a good idea for you to give it a try. It’s an easy supplement to take, and absorbs quickly into your body. However, be careful not to take CoQ10 if you are taking any medication that might thin your blood. It is unlikely to happen, but make sure to consult your doctor if you start taking CoQ10 and experience weird symptoms. 

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Leslie Waterson

Leslie has been passionately involved in the health and fitness industries for over a decade. She is constantly reviewing the latest scientific research and studies in order to take a research-backed approach to lifestyle optimization. Her main areas of interest include nutrition and supplementation. Leslie shares her findings on Fitness Clone to help other health enthusiasts choose the products and routines that will help them achieve their goals.