Research-Based

How Long Does It Take For Probiotics To Work?

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By Meghan Stoops, RDN

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

how long does it take for probiotics to work

Gut health has captured widespread attention lately. Walking through any grocery store, you’ll encounter countless products claiming to contain probiotics, prebiotics, or “support gut health” somehow, but what does this actually mean? What exactly are probiotics? And how long does it take for probiotics to work?

These are the questions we’ll answer in this comprehensive guide. Let’s dive in.

What Are Probiotics?

Probiotics are beneficial bacteria that inhabit our gut and play a crucial role in our health. You can also find probiotics in various foods, particularly fermented ones like yogurt, kefir, sauerkraut, tempeh, and kimchi.

probiotic food

While incorporating these foods to support gut health has been discussed for over a century, the term “Probiotic” is relatively new. You may also encounter the term ‘prebiotic‘ — these are typically forms of dietary fiber that nourish gut bacteria so they can flourish.

Seven different probiotic strains are commonly found in products: Lactobacillus, Bifidobacterium, Saccharomyces, Streptococcus, Enterococcus, Escherichia, and Bacillus.

According to the American College of Gastroenterology, research suggests that certain probiotics may aid digestion and treat digestive issues such as diarrhea or irritable bowel syndrome (IBS), prevent autoimmune diseases, reduce vaginal and urinary tract infections, and even improve various skin conditions.

While the potential functions of probiotics appear extensive, more research is needed to fully understand their many roles in the human body.

Benefits of Probiotics

Beyond supporting digestive health, probiotics also provide many other beneficial functions throughout the body, including:

  • Manufacturing vitamins (including vitamin K and B vitamins)
  • Reducing childhood and adult obesity rates
  • Reducing chronic disease risk, including type 2 diabetes, metabolic syndrome, heart disease, depression, and Alzheimer’s disease.
  • Reducing systemic inflammation
  • Improving blood pressure and cholesterol levels
  • Reducing depression and anxiety
  • Strengthening immune function
  • Preventing cavities and periodontal disease
  • Reducing hay fever incidence
  • Improving asthma symptoms
  • Improving atopic dermatitis
  • Reducing allergy symptoms
  • Improving acne
  • Reducing upper respiratory infection rates

probiotics supports digestive health

It’s important to note that many studies supporting these claims are small-scale or conducted on animal subjects and require further human research. Additionally, some conditions respond better to specific probiotic strains, while others may prove less effective.

How Long Does It Take for Probiotics to Work?

If you’re taking a probiotic supplement for optimal results, you should take it daily at approximately the same time. But how long before you see positive effects?

With consistent probiotic intake, the timeframe for noticing benefits varies based on several factors: your reason for taking probiotics, the specific strain used, and the colony-forming units (CFUs) in your supplement.

taking probiotic supplement

For general health maintenance, you may not notice immediate changes in how you feel. However, for specific digestive issues like diarrhea, you may experience positive effects more quickly.

A systematic review of randomized and quasi-randomized controlled trials found that probiotics combined with rehydration therapy showed improvement in adults and children with acute infectious diarrhea within just 2 days.

Another 2011 study involving sixty-seven IBS patients showed that Saccharomyces Boulardii supplementation produced significant symptom improvement within one month.

While Saccharomyces Boulardii demonstrated improvements for IBS symptoms, the same results wouldn’t necessarily apply to upper respiratory infections due to strain-specific benefits.

Those taking probiotics inconsistently or using supplements with lower CFU counts may require longer to notice health improvements, if any occur at all.

Why Probiotics Take Longer To Work Than Vitamins

Like vitamins, probiotics support overall health and well-being. However, given their role in promoting gut health, probiotics remain in your intestines rather than being rapidly absorbed into the bloodstream like vitamins.

Multiple variables affect how quickly probiotics take effect. With a high-quality, potent supplement containing billions of microorganisms with high CFU counts, proven to withstand harsh acidic gut conditions, you might feel effects within hours of intake.

However, several factors can slow probiotic effectiveness: substance use or abuse, inadequate diet and exercise, your initial microbiota state (existing gut microbe populations), and consuming low-quality probiotics.

How to Make Probiotics More Effective

Probiotics work most effectively when paired with a healthy diet and lifestyle. Taking a probiotic supplement without considering these lifestyle factors won’t provide significant benefits — similar to how taking a multivitamin doesn’t dramatically improve health without balanced meals.

You should also include prebiotics to support healthy gut flora. If you’re consuming probiotic-rich foods or supplements, ensure they’re thriving in your gut. Excellent prebiotic sources include chicory root, dandelion greens, Jerusalem artichoke, garlic, onions, leeks, asparagus, bananas, and apples.

probiotic rich food apple

When choosing probiotic supplements, select carefully. Most probiotics are regulated as supplements rather than food, meaning they’re not FDA-regulated. This allows manufacturers to make claims without requiring supporting research.

Always choose supplements from trusted manufacturers. Look for 3rd party testing on labels. Ensure the product contains substantial probiotics without unnecessary fillers or additives. Probiotics are measured in colony-forming units (CFUs) — the total live strains expected per serving. This varies by product. Researchers recommend quality probiotic supplements contain at least 1,000,000 CFUs per gram (or 106) or more for positive effects.

Finally, is there an optimal time for probiotic supplementation? Experts suggest morning before meals or evening before bed may be ideal, when stomach acid levels are lowest; however, this depends on strain type, and robust research hasn’t confirmed these claims. This timing theoretically helps beneficial bacteria reach your digestive tract unharmed.

Ultimately, what matters most is when you’re most likely to take them consistently. Whether morning or evening, daily consistency at the same time ensures optimal results. Occasional use won’t yield significant benefits.

Choosing A Probiotic

Bacterial diversity is essential for gut health. Selecting the right probiotic depends entirely on your intended use. Most people choose probiotics for the following reasons:

To Relieve Constipation And Irritable Bowel Syndrome (IBS)

Several studies demonstrate that certain probiotic strains in supplements can reduce constipation pain for both children and adults. Look for probiotics containing B. lactis, B. longum, S. cerevisiae.

To Supplement Against Diarrhea

Diarrhea — characterized by loose-to-liquid bowel movements occurring more frequently than normal — can be effectively treated with probiotics. Beneficial strains include Lactobacillus rhamnosus GG, Lactobacillus acidophilus, and Lactobacillus bulgaricus.

To Help You Lose Weight

Growing evidence suggests probiotics may significantly impact body weight! If you’re concerned about belly fat, these “good bacteria” appear beneficial, with some studies showing 8.5% fat loss in that area. Look for probiotics containing Lactobacillus gasseri, Lactobacillus rhamnosus, and the combination of Lactobacillus rhamnosus and Bifidobacterium lactis for weight reduction support.

To Support Heart Health

Beyond digestive benefits, probiotics may help reduce heart disease risk. Specific bacterial strains studied for cholesterol reduction include Lactobacillus acidophilus, Bifidobacterium longum, and Lactobacillus reuteri.

To Boost Immunity

Probiotics strengthen your body’s defenses against allergies, infections, and even cancer by balancing gut bacteria and reducing inflammation. Effective strains include Lactobacillus GG, Lactobacillus crispatus, Lactobacillus gasseri, Bifidobacterium bifidum, and Bifidobacterium longum.

To Promote General Health

Probiotics aren’t limited to targeting specific diseases — you can take them to support overall health and wellness. For this purpose, choose probiotics containing Bifidobacterium bifidum.

When shopping for authentic probiotics, ensure your chosen product contains live and active bacterial cultures, clearly indicated on packaging.

Best Probiotics On The Market

If you’re ready to research quality-tested probiotic products but unsure where to begin, always filter brands that align with your needs and lifestyle. Below are our picks for the best probiotic supplements.

Gundry MD Probiotics

24 Strain Probiotic

Committed to a more “gut-friendly” diet? Gundry MD 24 Strain Probiotic might be your ideal choice!

This supplement prioritizes digestive wellness by providing one of the most potent probiotic supplements available. The brand created a specialized formula combining twenty-four (24) unique probiotic strains, with each capsule containing thirty (30) billion CFUs to help your beneficial bacteria thrive.

Accommodating even the most restrictive diets, this product is vegetarian and both dairy and caffeine-free. If you’re unsatisfied with the results, the brand offers a 100% money-back guarantee for 90 days!

USE CODE “FITNESSCLONE” FOR 10% OFF 24 STRAIN PROBIOTIC

 

Seed Daily Synbiotic

seed Daily Synbiotic

What’s better than being prebiotic? Being both prebiotic and probiotic!

Found in many fruits and vegetables, prebiotics are microorganisms that act as fertilizers, stimulating healthy bacteria growth in the gut.

Essentially serving as “food for your beneficial bacteria,” Seed Daily Synbiotic extends beyond gastrointestinal health to promote overall wellness, benefiting cardiovascular, dermatological, immune, metabolic, and reproductive health.

Seed pioneered the first synbiotic supplement with strains that increase folate production (the natural form of folic acid) within the body.

Beyond being dairy-free, gluten-free, and soy-free, its ingredients perfectly suit vegan, vegetarian, and ketogenic diets.

BONUS: Seed Daily Synbiotics champions sustainability. Made from mushrooms and cornstarch, the brand’s packaging includes a systematic guide to help you transition into your new regimen.

GET THE BEST PRICE ON SEED DAILY SYNBIOTIC

 

Silver Fern’s Ultimate Probiotic

Ultimate Probiotic Supplement

Did you know “bad bacteria” thrives on sugar and contributes to sugar cravings? Silver Fern’s Ultimate Probiotic works by replacing harmful bacteria with beneficial ones, eventually reducing unwanted sugar cravings and improving nutrient absorption!

DNA-verified to ensure the correct strains address gut issues, it also supports immune and mental health by working on Serotonin (your happiness neurotransmitter), primarily found in the gastrointestinal tract, effectively improving mood while reducing anxiety and depression.

The brand’s unique spore-form probiotics are 100% guaranteed to survive stomach acidity, ensuring all eight (8) billion CFUs reach your gut to perform their function.

BONUS: They’re currently offering a limited special price promotion!

GET THE BEST PRICE ON SILVER FERN’S ULTIMATE PROBIOTIC

 

Bottom Line

Extensive research exists on probiotic supplement benefits; however, much of this research involves specific strains and populations, requiring further study to determine optimal probiotic utilization for human health.

If you’re considering probiotic supplementation, choose products from credible sources containing high CFU counts. Take your probiotic supplement daily at consistent times. The timeframe for experiencing benefits varies based on your supplementation purpose, chosen strain, and CFUs per dose.

Before adding probiotics to your routine, always consult your healthcare provider. Immunocompromised individuals should avoid probiotic supplements.

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Meghan Stoops, RDN

Meghan Stoops is a Registered Dietitian and licensed Nutritionist with a bachelor’s in Dietetics from San Diego State University. Meghan developed an interest in dietetics early on through her own personal struggles with nutrition misinformation. She began doing her own research, which sparked her passion for nutrition and it’s impact on our physical and mental health. Today, she takes take a non-diet, all-foods-fit approach to nutrition, and is devoted to teaching others that eating healthy does not mean restriction or sacrifice.