Arthrozene Review – Will This Supplement Benefit Your Joints?

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By Leslie Waterson

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

Arthrozene Review

About Arthrozene

Arthrozene is a natural joint health supplement manufactured by Fisico. Arthozene is intended to act as a 3 step solution to reducing joint discomfort and improving the function and flexibility of joints, to improve everyday life for individuals suffering from joint dysfunction. This supplement is made using natural products that are scientifically shown to be effective at alleviating joint complications. Additionally, it is GMP certified to ensure the safety and purity of its ingredients.

So, the only question is, is Arthrozene the right choice for your joints? There are many joint supplements out there, such as Instaflex Advanced and Tropical Oasis Joint Complete Premium, so how does Arthrozene stack up? Let’s take a closer look at this supplement and learn more in this Arthrozene review.

Arthrozene Supplement

Arthrozene Benefits 

Reduces Pain And Discomfort

Arthrozene is made from naturally sourced ingredients that have been scientifically shown to be effective at alleviating joint pain and reducing inflammation in the joints to reduce discomfort.

Slows Cartilage Breakdown

Arthrozene contains hyaluronic acids and collagen derived from chicken, which can help reduce the breakdown of joint cartilage that occurs in everyday life. It may also improve the strength of cartilage to help prevent joint disorders from developing.

Improved Flexibility And Mobility

Chicken Comb Extract helps to increase lubrication around joints, as Boswellia Serrata can reduce joint inflammation. This reduces the pain that can limit daily activities, and grants you better function of your limbs to increase mobility.

Arthrozene Benefits

Arthrozene Ingredients

AprèsFlex® Boswellia Serrata Extract (100mg)

Boswellia Serrata is a medicinal plant that is commonly used for its anti-inflammatory properties. Boswellia contains high amounts of boswellic acids, which inhibit the formation of leukotrienes, an inflammatory molecule found in the body. Boswellia has been researched as a possible treatment for osteoarthritis, and has been shown to be more effective at reducing pain related to osteoarthritis when compared to a placebo.

Mobilee® Natural Chicken Comb Extract (80mg)

Chicken Comb extract(CCE) is derived from chicken combs, which is the red, fleshy crest seen on top of chicken’s heads. Chicken combs are actually an organ, and made out of cartilaginous materials. It is naturally very high in hyaluronic acids, which keeps your joints lubricated. Supplemental CCE has been shown to reduce collagen degradation in cartilage, improves the synthesis of collagen in cartilage, and increases hyaluronic acid around the joints. All of these contribute to healthier joints, and can reduce pain while improving joint mobility.

B-2 Cool® Native Collagen Type 2 Extract (40mg) 

Native collagen type 2 is the primary component of joint cartilage tissue, and is what makes cartilage resistant to tension from stressors. B-2 Cool’s collagen is derived from avian sternum. Native collagen supplementation has been heavily researched as a treatment option for people suffering from arthritis and joint inflammation, and has been shown to cause significant improvements in arthritic symptoms.

Arthrozene Ingredients

Who Is Arthrozene Best For?

Arthrozene was made for people who suffer from chronic joint discomfort, who want a natural and effective treatment option. It is ideal for people with rheumatoid arthritis, osteoarthritis, or people who experience pain and poor mobility in their joints.

Arthrozene For Joints

How To Take Arthrozene

Take 1 capsule daily on an empty stomach with a glass of water.

Does Arthrozene Work? 

Each of the primary ingredients in Arthrozene have been researched as treatments for various joint disorders – There seems to be sufficient data to support the idea that Arthrozene may be effective at alleviating symptoms for some people. The ingredients in Arthrozene have the potential to improve various aspects of overall joint health, so it is likely to see a benefit even if you are not currently experiencing joint problems. While the manufacturers of Arthrozene claim it begins working in 5 days, it may take up to 90 days for people to begin seeing improvements from collagen supplementation.

Arthrozene Supplement Research

Is Arthrozene Safe?

There are no specific safety concerns regarding this product. Each ingredient has no known side effects, and are regarded as safe to take by everyone.  However, It is not recommended to take Arthozene if you are under 18 years of age, pregnant, or nursing.


  • Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6(6):312-321. Published 2009 Oct 9. doi:10.7150/ijms.6.312
  • Wei W, Zhang LL, Xu JH, et al. A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis. Arthritis Res Ther. 2009;11(6):R180. doi:10.1186/ar2870
  • Kalman, D.S., Heimer, M., Valdeon, A. et al. Effect of a natural extract of chicken combs with a high content of hyaluronic acid (Hyal-Joint®) on pain relief and quality of life in subjects with knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial. Nutr J 7, 3 (2008).

Where To Buy Arthrozene

Arthrozene is only available for purchase through or Amazon. The best price can be found at for $49.95 for 30 capsules ($1.66/capsule), and they offer discounted pricing if you purchase multiple bottles.

Arthrozene Website

While this product is a bit pricey, Arthozene also offers a 90-day satisfaction guarantee for a full refund if you are not completely satisfied with the product.

Overall Rating:
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Leslie Waterson

Leslie has been passionately involved in the health and fitness industries for over a decade. She is constantly reviewing the latest scientific research and studies in order to take a research-backed approach to lifestyle optimization. Her main areas of interest include nutrition and supplementation. Leslie shares her findings on Fitness Clone to help other health enthusiasts choose the products and routines that will help them achieve their goals.