Best Liquid Probiotic – 4 Top Choices

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By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

Best Liquid Probiotic

Gut health issues are seemingly becoming more and more common today. Maybe it’s the food we’re eating, the stressful, hectic lifestyles, abundant toxins, or who knows what else.

But the bottom line is that many people are looking to improve their gut health. And often, one of the first things people do is try out a probiotic supplement. 

These are usually capsules or pills. But recently, there are now a variety of liquid probiotics available for people who want to drink their supplements.

And in this article, we’re going over the best liquid probiotic supplements so you know which ones to buy for optimal results!

Best Liquid Probiotic Supplements

Our top three liquid probiotic supplements are:

  • Manna Liposomal Probiotic
  • Athletic Greens 
  • Mary Ruth’s Liquid Probiotic
  • Entegro Health Flourish

Manna Liposomal Pre+Probiotic

Best Overall

Manna Liposomal Pre+ Probiotic earns the top overall spot for liquid probiotic supplements. This well-crafted formula contains 40 Billion CFU from eight different well-researched strains of probiotics for gut health enhancement. On top of that, they use inulin, which is a prebiotic fiber to promote good bacteria growth and gut health.

Manna Liposomal Pre+ Probiotic also uses NANOFUSE® liposomal delivery technology to enhance ingredient absorption and bioavailability by up to 10x compared to conventional formulas. 

Plus, it’s vegan, third-party lab-tested for safety and purity, non-GMO, and cGMP. 

manna liposomal curcumin

Athletic Greens

Best All-In-One Supplement

Athletic Greens (AG1) contains many gut-supporting ingredients, including 7 Billion CFU of probiotics, digestive enzymes, and prebiotic fibers.

And Athletic Greens is so much more than a gut health/probiotic too. In fact, the formula has 75 ingredients, including healthy doses of vitamins, minerals, superfoods, greens, and herbs. This may provide other benefits for energy, immunity, stress management, detoxing, and more.

It’s not a liquid per se, but comes as a powder so you can easily mix it with water for a quick drink.

AG1 is also NSF Certified for Sport, non-GMO, and free from artificial flavors, sweeteners, colors, and preservatives. 

athletic greens ag1

Mary Ruth’s Organic Liquid Probiotic

Most Convenient

Mary Ruth’s Organic Liquid Probiotic is a highly convenient and beneficial liquid probiotic supplement. Each serving contains 3g of probiotics to nourish the digestive tract and gut microbiome. They sourced the ingredients from 12 different organic strains. And it also comes with a dropper so you can take your serving anytime, anywhere. 

Mary Ruth’s Organic Liquid Probiotic is USDA Organic, vegan, non-GMO, cGMP, and free from the top 8 allergens. 

mary ruths organic liquid probiotic

Entegro Health Flourish

Best Value

If you’re looking for the most bang for your buck, Entegro Health Flourish probiotic may be worth buying. It has 8 Billion CFU from Lactobacillus, Bifidobacterium, and other probiotic strains. 

They use an all-natural fermentation process and even include molasses in the ingredients so the good bacteria can feed off it and continue to thrive. 

And Entegro Health Flourish is only $34.95 for 32 servings, making it highly affordable. All it takes is one tablespoon daily.

entegro health flourish

What are Liquid Probiotic Supplements?

Liquid probiotic supplements are products with probiotics (and usually other ingredients for gut health/overall health) typically immersed in a liquid such as water or oil. 

They’re designed to be a quick and easy way to get in probiotics and other nutrients to support digestion and gut health.

As you may know, probiotics are widely available as pills or capsules too. But some people may want liquid probiotics instead because they may be easier on the stomach, more convenient, and/or simply preferred over the other forms. 

Benefits of Liquid Probiotics

Liquid probiotics have the same potential benefits as regular probiotics, which includes:

  • Improved Digestion
  • Balanced Gut Health
  • Enhanced Immunity
  • Total Wellness Support

Improved Digestion

Liquid probiotics contain a variety of probiotic strains, which have a beneficial effect in our gut and digestive tract. They may help secrete more digestive enzymes and improve overall digestion, which could also lead to decreased bloating, gas, and other symptoms. 

Balanced Gut Health

Probiotics are naturally found in our gut, and a lack of these good bacteria may spell disaster for gut health. But the liquid probiotics can introduce more of these good bacteria in the gut, which may also help get rid of pathogenic bacteria, improve gut barrier function, and enhance intestinal function.

Altogether, this may lead to a stronger, healthier, more protected gut. 

Enhanced Immunity

Liquid probiotics may also enhance immunity, mainly because the gut is connected to the immune system. So, by improving gut health, liquid probiotics may enhance the gut-immune connection and lead to a healthier immune system. 

Total Wellness Support

The gut is important for overall health too. And as we continue to learn more about it, we’re seeing just how important gut health is for inflammation, metabolism, immunity, brain function, and other areas.

Thus, liquid probiotics could offer total wellness support by enhancing gut health and boosting all of those gut-body connections. 

Liquid Probiotic For Total Wellness

How to Choose the Best Liquid Probiotic

There are many probiotics out there, which makes it essential to know how to pick the best ones. This is especially true since there have been a lot of probiotics in the past that were simply ineffective and improperly formulated.

Now, there aren’t as many liquid probiotics as regular probiotics, but it still is obviously important to know how to pick the best ones!

One of the things to consider is total CFU count, which is the amount of good bacteria you’re getting. There is a huge range in CFU dosage, with anywhere from less than 1 Billion CFU all the way to 100 Billion or more.

Generally, a moderate dosage of 5 Billion to 20 Billion is effective, although upwards of 40 to 50 Billion CFU may provide quicker and/or more noticeable benefits. For most people, going in the 5 to 50 Billion CFU range seems reasonable and effective.

As with all supplements, make sure that the liquid probiotic you’re getting is:

  • Made in a cGMP, FDA-registered facility
  • Tested for purity and potency (ideally through a third party)

Also, most of the time it’s best to have a liquid probiotic that has a fully transparent label. But it’s okay if a supplement has a proprietary blend IF that blend includes only probiotic strains, since those have very similar benefits. 

Just make sure they put the total dosage of the blend on there, and that there aren’t any herbs or different ingredients in the blend. Those should be listed out separately.

Depending on your preferences and needs, you may also need to make sure that a liquid probiotic is:

  • Organic
  • Non-GMO
  • Free from one or more of the major allergens
  • Free of artificial ingredients
  • Made without added sugar

Lastly, you may get more benefits from products that have other ingredients, such as prebiotics, postbiotics, or various herbs. For some, a supplement with just probiotics is fine. But prebiotics often work in tandem with probiotics to provide synergistic effects on gut health.

And there are also various herbs, vitamins, and other ingredients that can further support gut health. But the prebiotics and probiotics are likely the most direct. 

Additional Information (FAQ)

If you have any other questions or are still wondering about liquid probiotics, check out the below section for more important info.

Do liquid probiotics work?

Like regular probiotics, individual results may vary with liquid probiotics. This is because gut problems are complex and have several factors. But in general, if someone’s gut problems are due to a lack of good bacteria, liquid probiotics may work to improve gut health by restoring balance to the gut microbiome.

How long does it take for liquid probiotics to work?

Some people may notice rather quick effects of liquid probiotics, such as within one or two days. But for the best results, liquid probiotics typically take at least a couple weeks, if not a couple months. 

Do liquid probiotics need to be refrigerated?

This depends on the product. For example, Manna Liposomal Pre+ Probiotic doesn’t require refrigeration, but other supplements may. That’s why you should always check the label, or ask the makers if they don’t specifically state.

How do you take liquid probiotics?

Generally, most liquid probiotics can be taken as is (in shot or packet form) or mixed in with water or another beverage of choice.

Are liquid probiotics safe?

Probiotics are generally safe and free of side effects for most people. But some people may experience side effects, especially initially, such as:

  • Bloating
  • Gas
  • Upset stomach

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Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.