CX8 Review – Should You Use This Supplement?

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By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated

cx8 review

With heart disease still the number one health issue, many people look for ways to manage their heart health and support optimal cardiovascular functioning. 

We’ve also seen a growing interest in heart support supplements, which are designed to target key cardiovascular risk factors and reduce the chance of heart problems down the line. 

Of course, it’s essential to see that these supplements are actually safe, effective, and worthwhile! And in this review, we’re covering a heart supplement called CX8.

In this CX8 review, you’ll discover the key ingredients in the formula, possible benefits, how it works, and our overall thoughts on how effective it is.

About CX8

CX8 is advertised as an advanced heart health support supplement, created by Xtend-Life, the same makers as Xtend-Life Total Balance.


It was developed in part by Warren Matthews (also the founder of Xtend-Life) who had to have open heart surgery, despite having seemingly great health according to standard medical tests. 

Matthews then decided to dig into the research, where he uncovered some causes of “hidden” heart risk factors, and then traveled the world and met with bioengineers, scientists, physicians, and other experts to understand what ingredients are most effective at preventing heart health problems. 

The end result was CX8, which is formulated with 8 clinically-researched, bioactive ingredients which are designed to work synergistically to address the primary causes of heart and artery dysfunction. Within this, it aims to address some often overlooked heart risk factors, such as arterial calcification and inflammation. 

CardioOmegia, CyanthOX, and DeltaGold are just a few of the ingredients featured in CX8 designed to offer superior support for heart health and cardiovascular function.

CX8 Benefits

CX8 is designed to benefit all-around heart health. In particular, CX8 is advertised to target these five areas:

  • Reduced Arterial Calcification
  • Improved Circulation
  • Decreased Inflammation
  • Increased Stem Cell Production
  • Balanced Cholesterol Levels
CX8 Benefits

Reduced Arterial Calcification

Arterial calcification can harden and narrow the arteries, which makes heart problems more likely to occur.

CX8 claims to reduce arterial calcification by using natural decalcifiers such as Menaq7 PURE vitamin K2. 

Improved Circulation

Impaired circulation can cause many symptoms ranging in severity, including milder ones such as cold feet and decreased energy, as well as way too severe ones like a higher chance of heart attacks.

CX8 is advertised to improve circulation and total body blood flow. They use Nattozimes nattokinase which they say improves arterial lining and enhances blood flow. Plus there’s vitamin D3, which is designed to further support overall heart health and circulation.

Decreased Inflammation

Chronic inflammation can lead to structural and functional changes in the cardiovascular system which can increase the risk of heart problems down the line.

Xtend-Life CX8 claims to decrease inflammation and oxidative stress, especially with natural anti-inflammatory ingredients such as rutin and Oxifend black currant polyphenols. 

Increased Stem Cell Production

Cells in the cardiovascular system can get damaged over time, which can cause many different heart issues.

CX8 has a unique benefit claiming to increase stem cell production with CyanthOx sea buckthorn extract. They say that this will help to replenish damaged cells in the cardiovascular system and improve overall heart function.

Balanced Cholesterol Levels

Elevated cholesterol levels (especially LDL cholesterol) can cause plaque build-up in the arteries which increases the chances of heart attack and other problems.

CX8 is advertised to help balance cholesterol levels, particularly by using DeltaGold tocotrienols as well as other natural compounds. They say this will increase HDL (the “good” cholesterol) while decreasing LDL ( the “bad cholesterol”). 

These five benefits surely are a great combination for overall heart health and to reduce the risk of heart problems.

But are these claims by CX8 actually backed up?

Read on to find out as we review CX8’s ingredients and possible benefits.

CX8 Ingredients

CX8 has 8 active ingredients (which is partly where the name “CX8” comes from”. It’s a mix of herbal extracts and vitamins, several of which are trademarked forms.

Below are all 8 active ingredients:

  • Vitamin D3
  • MenaQ7 PURE Vitamin K2
  • CardiOmegia Sea Buckthorn Extract
  • CyanthOX Sea Buckthorn Fruit Extract
  • DeltaGold Tocotrienol Complex
  • Rutin
  • Nattozimes Protease
  • OxiFend Black Currant Extract
CX8 Supplement Facts

Vitamin D3 (25mcg) and Menaq7 PURE Vitamin K2 (180mcg)

The two vitamins in CX8 are vitamin D3 and vitamin K2 (which comes from the trademarked form Menaq7 Pure).

We grouped these together because vitamin D and vitamin K work synergistically with each other to improve heart health

Specifically, vitamin D and vitamin K both need each other and work together to prevent arterial calcification. And this can lead to a decreased risk of heart attack and other cardiovascular events. 

Not to mention both vitamin D and vitamin K are generally anti-inflammatory. 

CardiOmegia Sea Buckthorn Extract (630mg)

CardiOmegia is actually one of two trademarked forms of sea buckthorn extract in this product. This particular form is standardized to contain a high level of omega-7 fatty acids.

And omega-7 is a critical fatty acid that may help to decrease inflammation, improve cholesterol, support healthy blood sugar and triglycerides, and support other aspects of metabolic health.

In fact, a clinical study on CardiOmegia shows that it significantly reduced inflammation, decreased LDL cholesterol, and improved HDL cholesterol, all of which may support heart and metabolic health.

CyanthOX Sea Buckthorn Fruit Extract (500mg)

Another trademarked form of sea buckthorn extract is CyanthOX. However, this one is specifically crafted to contain a high level of proanthocyanidins, which are a group of anti-inflammatory compounds. 

In a clinical trial, CyanthOX was shown to stimulate different types of stem cells that contribute to anti-aging and anti-inflammatory effects, as well as to enhance blood vessel health and circulation. 

Basically, it helped to increase heart cell function and repair any damage.

DeltaGold Tocotrienol Complex (300mg)

DeltaGold is a trademarked form of various tocotrienols, which are chemicals found in the vitamin E family that have antioxidant effects.

Clinical research on DeltaGold shows that it can decrease inflammation and support healthy cholesterol, mainly by lowering LDL and increasing HDL. 

Rutin (100mg)

Rutin is a flavonoid, so it is a strong antioxidant and anti-inflammatory compound. It also seems to support blood vessel health and general cardiovascular function, which is in part due to its anti-inflammatory roles.

Nattozimes Protease (115mg)

Nattozimes is a trademarked blend of protease enzymes. It is designed to work like nattokinase, which is a natural enzyme derived from natto (a fermented soy food).

Nattozimes may support healthy circulation and may also reduce the risk of blood clots.

Oxi-Fend Black Currant Extract (50mg)

Oxi-Fend is a trademarked form of blackcurrant extract, which is an herbal extract that’s high in polyphenols and other antioxidants.

Due to this, Oxi-Fend may decrease oxidative stress and inflammation, which generally supports blood vessel health and cardiovascular function. 

Does CX8 Work?

Overall, it seems probable that CX8 will work for heart health support.

The CX8 formula is really high-quality and includes many clinically-researched ingredients, including the trademarked forms that have specific clinical evidence behind them.

On top of that, pretty much every ingredient is dosed optimally and in line with the studies. So this means that CX8 is more likely to actually give you the benefits, such as balanced cholesterol, reduced inflammation, improved circulation, and decreased arterial calcification.

Looking it over, all claims of CX8 are supported by research.

However, even with this said, we of course can’t guarantee that CX8 will prevent any and all heart issues. And it takes time to work. 

But CX8 definitely seems to be supportive of heart health and may very well reduce the risk of heart problems. We just can’t guarantee it for various reasons.

CX8 Key Ingredients

How Does CX8 Compare?

Generally, CX8 is one of the best heart health supplements we’ve come across. This is because it includes several well-researched ingredients, uses optimal doses, and has multiple benefits that make it a versatile and comprehensive heart support product. 

Many times heart health supplements will use subpar ingredients, ineffective doses, and/or proprietary blends, which decreases the overall quality and potential effectiveness.

Who is CX8 Best For?

CX8 is best for individuals who want a comprehensive heart support formula to improve heart function and possibly reduce the risk of heart problems down the line.

It is specifically advertised for adults over 40, but any adult who wants to support a healthy heart may benefit.

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  • Formula includes a mix of herbal extracts and vitamins
  • Made in a cGMP, FDA-registered facility
  • Benefits arterial calcification, circulation, inflammation, and more

How to Take CX8

CX8 comes in capsule form. You are instructed to take one serving (three capsules) daily, preferably at least one hour before or after a meal for optimal results.

Is CX8 Safe?

CX8 is generally a well-formulated supplement that abides by standards for quality and safety. There are possible side effects from the various ingredients, which include:

  • Upset stomach & digestive symptoms
  • Increased risk of bleeding in some people
  • Headache

CX8 is made in a cGMP, FDA-registered facility and is ISO 9001 Accredited.  It is vegan, gluten-free, and vegetarian. 

Where to Buy CX8

You can buy CX8 on Xtend-Life’s website.

CX8 Website

There are 30 servings (90 capsules) per bottle of CX8, which costs $69.95 ($2.33/serving).

This is a pretty high-priced supplement, but you also have to consider the ingredient quality, doses, and other aspects that make CX8 likely better than other supplements. 

It would be nice if they had a subscription option though.

CX8 also has a massive 365-Day Money-Back Guarantee, so you have plenty of time to see if it works for you (and to return it if you’re not satisfied).

Verdict: CX8 Review

CX8 by Xtend-Life is one of the most well-formulated heart support supplements out there. The CX8 formula contains 8 well-researched ingredients, including several trademarked forms that have specific clinical research.

And most of the CX8 ingredients are dosed at a high level to promote the greatest effects. Overall, CX8 seems likely to offer many heart health benefits, such as reduced arterial calcification, decreased inflammation, and improved blood flow.

It’s not a cheap product, but the overall value likely makes it justified, especially for people who want to take it on a consistent, long-term basis.

Overall Rating:
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Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.